2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)benzonitrile

2-Fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)benzonitrile, identified by CAS 3028866-48-7, is a sophisticated organic compound with the molecular formula C14H17BFNO2 and a molecular weight of 261.10. It incorporates a fluorine atom and a methyl group on a benzonitrile core, alongside a pinacol boronic ester moiety. This combination of functional groups makes it a valuable intermediate in synthetic chemistry. The boronic ester group is highly reactive in palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds with aryl halides or triflates. The benzonitrile unit provides a nitrile functional group, which can be further transformed, while the fluorine and methyl substituents offer opportunities for fine-tuning electronic and steric properties in target molecules. This compound is suitable for research and development applications requiring precise molecular construction.

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