3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)aniline

This compound, with CAS 510771-54-7, is a highly functionalized aniline derivative incorporating a 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl (pinacol boronic ester) group and a trifluoromethyl group on a phenyl ring. The boronic ester moiety makes it an excellent substrate for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The trifluoromethyl group can impart unique electronic and steric properties, while the aniline group provides a site for further derivatization, such as acylation or diazotization. It is primarily used as a synthetic intermediate in the development of novel chemical entities for research purposes.

• Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information before use.