Chemical Identity
Molecular Formula
C6H4BBrF3NO2
Molecular Weight
269.81 g/mol
Exact Mass
268.94706
PubChem CID
46739155
IUPAC Name
[5-bromo-2-(trifluoromethyl)-4-pyridinyl]boronic acid
SMILES String
OB(O)c1cc(C(F)(F)F)ncc1Br
Names & Synonyms
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External Identifiers
Catalog Overview
5-Bromo-2-trifluoromethylpyridine-4-boronic acid (CAS: 1072951-57-5) is a highly functionalized pyridine derivative. It features a pyridine core substituted with a bromine atom, a trifluoromethyl group, and a boronic acid moiety. This combination of functional groups makes it a valuable intermediate in various synthetic routes, particularly in cross-coupling reactions like Suzuki-Miyaura coupling, for constructing complex pyridine-containing molecules. Its trifluoromethyl group can impart unique electronic and steric properties, while the bromine and boronic acid groups offer sites for further derivatization.
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
5-Bromo-2-trifluoromethylpyridine-4-boronic acid (CAS: 1072951-57-5) is a highly functionalized pyridine derivative. It features a pyridine core substituted with a bromine atom, a trifluoromethyl group, and a boronic acid moiety. This combination of functional groups makes it a valuable intermediate in various synthetic routes, particularly in cross-coupling reactions like Suzuki-Miyaura coupling, for constructing complex pyridine-containing molecules. Its trifluoromethyl group can impart unique electronic and steric properties, while the bromine and boronic acid groups offer sites for further derivatization. It is intended for research use only.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White to off-white crystalline solid
Physical State
Solid
Melting Point
202.0 °C
Boiling Point
288.0 °C
Density
1.7 g/cm³
Water Solubility
0.0708 mol/L
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. Refer to the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. Store in a cool, dry place, away from incompatible materials. For research use only.
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