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(4-(Piperidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid

CAS 2256708-80-0Formula C12H15BF3NO2MW 273.06PubChem 168437302

This compound is a functionalized boronic acid derivative featuring a piperidin-3-yl group and a trifluoromethylphenyl moiety. It is primarily used as a building block in organic synthesis for research purposes.

Loading RDKit molecule structure...
InChIKey: FQEJUYJBNLHSAC-UHFFFAOYSA-NC12H15BF3NO2 | MW 273.06

Chemical Identity

Molecular Formula

C12H15BF3NO2

Molecular Weight

273.06 g/mol

Exact Mass

273.114793

PubChem CID

168437302

IUPAC Name

[4-piperidin-3-yl-3-(trifluoromethyl)phenyl]boronic acid

SMILES String

OB(O)c1ccc(C2CCCNC2)c(C(F)(F)F)c1

External Identifiers
CS-34237

Catalog Overview

(4-(Piperidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid, with CAS number 2256708-80-0, is a versatile organic compound. It incorporates a boronic acid functional group, which is highly valuable in Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The molecule also contains a piperidine ring, a common heterocyclic scaffold in medicinal chemistry, and a trifluoromethyl group, often used to enhance lipophilicity and metabolic stability in drug discovery. This combination of functional groups makes it a useful intermediate for synthesizing complex molecules in pharmaceutical and...

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Read more catalog context

(4-(Piperidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid, with CAS number 2256708-80-0, is a versatile organic compound. It incorporates a boronic acid functional group, which is highly valuable in Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The molecule also contains a piperidine ring, a common heterocyclic scaffold in medicinal chemistry, and a trifluoromethyl group, often used to enhance lipophilicity and metabolic stability in drug discovery. This combination of functional groups makes it a useful intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White to off-white powder or crystalline solid

Physical State

Solid

Melting Point

150.0 °C

Boiling Point

380.0 °C

Density

1.3 g/cm³

Water Solubility

Slightly soluble to insoluble

Flash Point

200.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information.

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