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tert-Butyl (2R,4S)-2-(bromomethyl)-4-methylpyrrolidine-1-carboxylate

CAS 2306253-78-9Formula C11H20BrNO2MW 278.19PubChem 155905493

This is a chiral pyrrolidine derivative featuring a bromomethyl group and a tert-butyl carbamate protecting group. It serves as a versatile building block in organic synthesis, particularly for constructing complex molecules with defined stereochemistry.

Loading RDKit molecule structure...
InChIKey: WUARHZWSFMJLHR-DTWKUNHWSA-NC11H20BrNO2 | MW 278.19

Chemical Identity

Molecular Formula

C11H20BrNO2

Molecular Weight

278.19 g/mol

Exact Mass

277.06774

PubChem CID

155905493

SMILES String

C[C@H]1C[C@H](CBr)N(C(=O)OC(C)(C)C)C1

External Identifiers
starbld0031521

Catalog Overview

tert-Butyl (2R,4S)-2-(bromomethyl)-4-methylpyrrolidine-1-carboxylate is a precisely structured organic compound with the molecular formula C11H20BrNO2 and a molecular weight of 278. 19 g/mol. It incorporates a pyrrolidine ring, a bromomethyl substituent at the 2-position, a methyl group at the 4-position, and a tert-butyl carbamate (Boc) protecting group on the nitrogen. The (2R,4S) stereochemistry indicates specific spatial arrangements of these groups, making it valuable for enantioselective synthesis.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

tert-Butyl (2R,4S)-2-(bromomethyl)-4-methylpyrrolidine-1-carboxylate is a precisely structured organic compound with the molecular formula C11H20BrNO2 and a molecular weight of 278.19 g/mol. It incorporates a pyrrolidine ring, a bromomethyl substituent at the 2-position, a methyl group at the 4-position, and a tert-butyl carbamate (Boc) protecting group on the nitrogen. The (2R,4S) stereochemistry indicates specific spatial arrangements of these groups, making it valuable for enantioselective synthesis. As a functionalized intermediate, the bromomethyl group offers reactivity for various coupling reactions, while the Boc group provides protection and can be selectively deprotected.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White solid

Physical State

Solid

Melting Point

65.0 °C

Boiling Point

280.0 °C

Density

1.35 g/cm³

Water Solubility

Slightly soluble

Flash Point

165.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

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1858121-36-4CAS 1858121-36-4
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1374653-11-8CAS 1374653-11-8

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 293399GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.