3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzonitrile

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzonitrile, identified by CAS 479411-95-5, is a sophisticated organic compound designed for research applications. It features a trifluoromethyl group, a cyano group, and a pinacol boronic ester moiety attached to a benzene ring. This strategic arrangement of functional groups makes it an exceptionally versatile chemical intermediate. Researchers can leverage the boronic ester for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The trifluoromethyl and cyano groups provide distinct electronic and steric properties, allowing for precise modification and fine-tuning of molecular characteristics in the synthesis of complex molecules, particularly relevant in medicinal chemistry, agrochemical development, and advanced materials research.

• Always handle 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzonitrile in a well-ventilated area or a chemical fume hood. Wear appropriate personal protective equipment, including chemical-resistant gloves, safety goggles or a face shield, and a lab coat. Avoid inhalation of dust or vapors and prevent contact with skin and eyes. In case of exposure, rinse immediately with plenty of water and seek medical advice. Store the compound in a cool, dry place, tightly sealed, and away from incompatible materials. Refer to the Safety Data Sheet (SDS) for comprehensive safety information and emergency procedures before use.