Chemical Identity
Molecular Formula
C13H17BF3NO2
Molecular Weight
287.09 g/mol
Exact Mass
287.130443
PubChem CID
119081512
SMILES String
Cc1ncc(C(F)(F)F)cc1B1OC(C)(C)C(C)(C)O1
Names & Synonyms
External Identifiers
Catalog Overview
2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridine is a highly functionalized pyridine derivative. It incorporates a methyl group at position 2, a trifluoromethyl group at position 5, and a pinacol boronic ester at position 3 of the pyridine ring. The pinacol boronic ester moiety makes it a valuable reagent for carbon-carbon bond formation, especially in Suzuki-Miyaura cross-coupling reactions, enabling the introduction of the substituted pyridine core into more complex molecular structures. The trifluoromethyl group can impart unique electronic and lipophilic properties to target molecules.
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridine is a highly functionalized pyridine derivative. It incorporates a methyl group at position 2, a trifluoromethyl group at position 5, and a pinacol boronic ester at position 3 of the pyridine ring. The pinacol boronic ester moiety makes it a valuable reagent for carbon-carbon bond formation, especially in Suzuki-Miyaura cross-coupling reactions, enabling the introduction of the substituted pyridine core into more complex molecular structures. The trifluoromethyl group can impart unique electronic and lipophilic properties to target molecules. This compound is intended for research use only.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White to off-white crystalline powder
Physical State
Solid
Melting Point
110.0 °C
Boiling Point
300.0 °C
Density
1.2 g/cm³
Water Solubility
Slightly soluble
Flash Point
180.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood. Avoid inhalation, ingestion, and skin contact. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information.
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
Related CAS / Similar Products
Recommended application cues
Catalog discovery cues, not supplier-verified claims.
Related HS Code / Compliance
Compliance cues are non-linked reference tags and require shipment review.