5-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine

5-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine is a sophisticated organic compound characterized by a pyridine core substituted with a methyl group, a trifluoromethyl group, and a 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl (pinacol boronate) moiety. With a molecular formula of C13H17BF3NO2 and a molecular weight of 287.09, this compound serves as a highly reactive and versatile intermediate. The pinacol boronate group is particularly useful for palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds. The trifluoromethyl group often enhances lipophilicity, metabolic stability, and binding affinity in drug discovery contexts, while the pyridine ring is a common scaffold in pharmaceuticals and agrochemicals. This compound is primarily intended for research and development applications.

• Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. Refer to the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. Store in a cool, dry place, away from incompatible materials.