Chemical Identity
Molecular Formula
C14H17BClNO2
Molecular Weight
277.55 g/mol
Exact Mass
277.104087
PubChem CID
133662221
IUPAC Name
3-chloro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
SMILES String
Cc1c(Cl)cc(C#N)cc1B1OC(C)(C)C(C)(C)O1
External Identifiers
Catalog Overview
3-Chloro-2-methyl-5-cyanophenylboronic acid pinacol ester, with CAS 2223033-24-5, is a highly functionalized arylboronic acid pinacol ester. This compound serves as a valuable intermediate in synthetic chemistry, particularly for constructing complex organic molecules. The pinacol boronic ester moiety is stable and readily participates in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura coupling, to form new carbon-carbon bonds. The presence of a chlorine atom and a cyano group on the aromatic ring provides additional handles for further chemical transformations, allowing for the introduction of diverse...
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
3-Chloro-2-methyl-5-cyanophenylboronic acid pinacol ester, with CAS 2223033-24-5, is a highly functionalized arylboronic acid pinacol ester. This compound serves as a valuable intermediate in synthetic chemistry, particularly for constructing complex organic molecules. The pinacol boronic ester moiety is stable and readily participates in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura coupling, to form new carbon-carbon bonds. The presence of a chlorine atom and a cyano group on the aromatic ring provides additional handles for further chemical transformations, allowing for the introduction of diverse functionalities into target molecules. It is intended for research use only.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White crystalline powder
Physical State
Solid
Melting Point
120.0 °C
Boiling Point
320.0 °C
Density
1.2 g/cm³
Water Solubility
Slightly soluble
Flash Point
160.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Refer to the Safety Data Sheet (SDS) for comprehensive safety information before use.
Related Products / Graph Discovery
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Related CAS / Similar Products
Similar products (text references)
Recommended application cues
Catalog discovery cues, not supplier-verified claims.
Related HS Code / Compliance
Compliance cues are non-linked reference tags and require shipment review.