3-Chloro-5-cyanophenylboronic acid, pinacol ester

3-Chloro-5-cyanophenylboronic acid, pinacol ester (CAS: 1212021-11-8) is an organoboron compound featuring a phenyl ring substituted with a chloro group, a cyano group, and a pinacol boronic ester. With a molecular formula of C13H15BClNO2 and a molecular weight of 263.53, this compound serves as a versatile building block in synthetic organic chemistry. The pinacol ester protects the boronic acid, enhancing its stability and ease of handling, while the chloro and cyano functionalities offer additional sites for further chemical transformations. It is primarily utilized as a functionalized intermediate in the synthesis of complex molecules for research purposes.

• When handling 3-Chloro-5-cyanophenylboronic acid, pinacol ester, researchers should: Wear appropriate PPE, including safety goggles, gloves, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation exposure. Avoid contact with skin and eyes; in case of contact, rinse immediately with plenty of water and seek medical advice. Avoid ingestion and inhalation. Store properly, keeping the container tightly closed in a cool, dry place, away from incompatible materials. Handle with care, as with many organic reagents, it may cause irritation. Consult the Safety Data Sheet (SDS) for detailed hazard information and precautions.