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2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine

CAS 2223041-89-0Formula C13H17BF3NO2MW 287.09PubChem 132398957

This compound is a pyridine derivative featuring a trifluoromethyl group and a pinacol boronic ester. It is primarily used as a versatile building block in organic synthesis, particularly for cross-coupling reactions, for research purposes.

Loading RDKit molecule structure...
InChIKey: WXTPADHCAZCMJV-UHFFFAOYSA-NC13H17BF3NO2 | MW 287.09

Chemical Identity

Molecular Formula

C13H17BF3NO2

Molecular Weight

287.09 g/mol

Exact Mass

287.130443

PubChem CID

132398957

SMILES String

Cc1nc(C(F)(F)F)ccc1B1OC(C)(C)C(C)(C)O1

Names & Synonyms

2-methyl-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridineWXTPADHCAZCMJV-UHFFFAOYSA-NH62182F758277Z2049945245
Show all synonyms
2-Methyl-6-trifluoromethylpyridine-3-boronic acid pinacol ester
External Identifiers
CS-32645CS-0368948EN300-1588789

Catalog Overview

2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine is an organoboron compound characterized by a pyridine core substituted with a methyl group, a trifluoromethyl group, and a pinacol boronic ester. The pinacol boronic ester moiety makes it a valuable reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The trifluoromethyl group introduces electron-withdrawing properties, which can influence the reactivity and electronic properties of target molecules. This compound serves as a key intermediate in the synthesis of complex organic molecules,...

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine is an organoboron compound characterized by a pyridine core substituted with a methyl group, a trifluoromethyl group, and a pinacol boronic ester. The pinacol boronic ester moiety makes it a valuable reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The trifluoromethyl group introduces electron-withdrawing properties, which can influence the reactivity and electronic properties of target molecules. This compound serves as a key intermediate in the synthesis of complex organic molecules, including potential pharmaceuticals and agrochemicals, for research and development purposes.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White to off-white solid

Physical State

Solid

Melting Point

105.0 °C

Boiling Point

280.0 °C

Density

1.3 g/cm³

Water Solubility

Insoluble

Flash Point

185.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid ingestion and skin contact. Store in a cool, dry place, away from incompatible materials. Always consult the Safety Data Sheet (SDS) for comprehensive safety information before handling.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 293339GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.