Chemical Identity
Molecular Formula
C13H17BF3NO2
Molecular Weight
287.09 g/mol
Exact Mass
287.130443
PubChem CID
132398957
SMILES String
Cc1nc(C(F)(F)F)ccc1B1OC(C)(C)C(C)(C)O1
Names & Synonyms
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External Identifiers
Catalog Overview
2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine is an organoboron compound characterized by a pyridine core substituted with a methyl group, a trifluoromethyl group, and a pinacol boronic ester. The pinacol boronic ester moiety makes it a valuable reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The trifluoromethyl group introduces electron-withdrawing properties, which can influence the reactivity and electronic properties of target molecules. This compound serves as a key intermediate in the synthesis of complex organic molecules,...
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2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine is an organoboron compound characterized by a pyridine core substituted with a methyl group, a trifluoromethyl group, and a pinacol boronic ester. The pinacol boronic ester moiety makes it a valuable reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The trifluoromethyl group introduces electron-withdrawing properties, which can influence the reactivity and electronic properties of target molecules. This compound serves as a key intermediate in the synthesis of complex organic molecules, including potential pharmaceuticals and agrochemicals, for research and development purposes.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White to off-white solid
Physical State
Solid
Melting Point
105.0 °C
Boiling Point
280.0 °C
Density
1.3 g/cm³
Water Solubility
Insoluble
Flash Point
185.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid ingestion and skin contact. Store in a cool, dry place, away from incompatible materials. Always consult the Safety Data Sheet (SDS) for comprehensive safety information before handling.
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