2,2,2-trifluoroethyl N-(3-ethynylphenyl)carbamate

2,2,2-Trifluoroethyl N-(3-ethynylphenyl)carbamate, identified by CAS 1087798-02-4, is an organic compound characterized by a trifluoroethyl carbamate moiety attached to a 3-ethynylphenyl group. Its molecular formula is C11H8F3NO2 and it has a molecular weight of 243.18 g/mol. This chemical serves as a versatile building block in synthetic chemistry, leveraging both the carbamate and ethynyl functionalities. The trifluoroethyl group can influence properties such as lipophilicity and metabolic stability, while the ethynyl group provides a reactive handle for various click chemistry reactions, Sonogashira couplings, and other alkyne-based transformations. It is valuable for researchers synthesizing complex molecules, including potential pharmaceutical intermediates or materials science compounds.

• Handle 2,2,2-trifluoroethyl N-(3-ethynylphenyl)carbamate in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including safety goggles, gloves, and a lab coat, to prevent skin and eye contact. Avoid inhalation of dust or vapors. In case of contact, rinse thoroughly with water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for comprehensive safety information before use.