Chemical Identity
Molecular Formula
C12H15BF3NO2
Molecular Weight
273.06 g/mol
Exact Mass
273.114793
PubChem CID
56924434
SMILES String
CC1(C)OB(c2cccnc2C(F)(F)F)OC1(C)C
Names & Synonyms
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External Identifiers
Catalog Overview
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine, identified by CAS 1383625-22-6, is a sophisticated organic intermediate. It features a pyridine core substituted with a trifluoromethyl group at position 2 and a pinacol boronic ester at position 3. The trifluoromethyl group imparts unique electronic properties, while the pinacol boronic ester is a highly stable and reactive moiety commonly employed in Suzuki-Miyaura cross-coupling reactions. This compound's structure makes it a valuable building block for introducing both trifluoromethylated pyridine scaffolds and boronic acid functionalities into...
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
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3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine, identified by CAS 1383625-22-6, is a sophisticated organic intermediate. It features a pyridine core substituted with a trifluoromethyl group at position 2 and a pinacol boronic ester at position 3. The trifluoromethyl group imparts unique electronic properties, while the pinacol boronic ester is a highly stable and reactive moiety commonly employed in Suzuki-Miyaura cross-coupling reactions. This compound's structure makes it a valuable building block for introducing both trifluoromethylated pyridine scaffolds and boronic acid functionalities into complex molecules during research and development.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White solid
Physical State
Solid
Melting Point
95.0 °C
Boiling Point
280.0 °C
Density
1.3 g/cm³
Water Solubility
Slightly soluble
Flash Point
135.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. This product is for research use only and not for human or animal therapeutic or diagnostic use.
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