CAS 220986-38-9Not a supplier-issued SDS

Preliminary Safety Reference

4H,5H-Pyrano[4,3-b]pyran-3-carbonitrile, 2-amino-4-(2-chloro-6-fluorophenyl)-7-methyl-5-oxo-

Preliminary reference disclaimer

This preliminary safety reference is generated from structured MolGraph catalog fields and public reference-style data. It is not a supplier-issued Safety Data Sheet and should not be used as a substitute for supplier-issued documentation, workplace safety review, transport classification, or regulatory compliance decisions. For supplier SDS or COA, submit a documentation request through MolGraph.

Identity

CAS Number

220986-38-9

Chemical name

4H,5H-Pyrano[4,3-b]pyran-3-carbonitrile, 2-amino-4-(2-chloro-6-fluorophenyl)-7-methyl-5-oxo-

Molecular formula

C16H10ClFN2O3

Molecular weight

332.71 g/mol

Synonyms

4H,5H-Pyrano(4,3-b)pyran-3-carbonitrile, 2-amino-4-(2-chloro-6-fluorophenyl)-7-methyl-5-oxo-; 2-amino-4-(2-chloro-6-fluorophenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile; 2-amino-4-(2-chloro-6-fluorophenyl)-7-methyl-5-oxo-4H,5H-pyrano[3,2-c]pyran-3-carbonitrile; AE-848/10130055; 2-amino-4-(2-chloro-6-fluorophenyl)-7-methyl-5-oxo-4H-pyrano[3,2-c]pyran-3-car bonitrile; 2-amino-4-(2-chloro-6-fluorophenyl)-7-methyl-5-oxo-4,5-dihydropyrano[4,3-b]pyran-3-carbonitrile

InChIKey

CHZLLSSWQZIJFJ-UHFFFAOYSA-N

PubChem CID

3122229

Hazard / GHS Reference

GHS Pictograms

GHS07

Catalog reference cue; confirm supplier documentation before use.

Handling & PPE

  • Handle in a well-ventilated area or fume hood.
  • Avoid inhalation, ingestion, and skin/eye contact.
  • Keep container tightly closed in a dry and well-ventilated place.
  • Store away from incompatible materials.
  • Ensure good laboratory hygiene practices are followed.
  • Use appropriate PPE such as lab coat, compatible gloves, and eye protection.
  • Wear respiratory protection if ventilation is inadequate or if there is a risk of dust/aerosol exposure.
  • Ensure eye wash stations and safety showers are available.
  • Gloves should be inspected prior to use.

First Aid / Accidental Release

  • In case of inhalation, move to fresh air. If not breathing, give artificial respiration.
  • For skin contact, wash with plenty of soap and water. Remove contaminated clothing.
  • In case of eye contact, rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • If swallowed, rinse mouth. Do NOT induce vomiting.
  • Seek medical attention according to institutional procedures if irritation or symptoms persist.
  • For spills, avoid dust or aerosol generation.
  • Evacuate personnel to safe areas.
  • Ensure adequate ventilation.
  • Collect spilled material using trained-lab procedures and appropriate tools.

Firefighting / Stability

  • Use extinguishing media appropriate for the surrounding fire.
  • Wear self-contained breathing apparatus for firefighting if necessary.
  • Wear full protective gear to prevent contact with skin and eyes.
  • Keep containers cool with water spray.
  • This material is considered stable under recommended storage conditions.
  • Avoid strong oxidizing agents.
  • Avoid strong acids and strong bases.
  • May react with incompatible materials.
  • No known hazardous decomposition products under normal conditions of storage and use.

Physical and Chemical Reference

Appearance

White to off-white solid

Catalog reference value; verify against supplier SDS before use.

Physical State

Solid

Catalog reference value; verify against supplier SDS before use.

Melting Point

200.0 °C

Catalog reference value; verify against supplier SDS before use.

Boiling Point

450.0 °C

Catalog reference value; verify against supplier SDS before use.

Density

1.5 g/cm³

Catalog reference value; verify against supplier SDS before use.

Water Solubility

Slightly soluble

Catalog reference value; verify against supplier SDS before use.

Flash Point

258.1 °C

Catalog reference value; verify against supplier SDS before use.

Vapor Pressure

Estimated very low; unit not specified

Catalog reference value; verify against supplier SDS before use.

Autoignition Temp

450.0 °C

Catalog reference value; verify against supplier SDS before use.

Transport / Shipment Review

HS6

293499

Preliminary catalog cue; verify before compliance decisions.

HS Code

293499

Source: catalog inference.

GHS Pictograms

GHS07

Preliminary catalog cue; verify before compliance decisions.

Compliance

standard-ruo

Preliminary catalog cue; verify before compliance decisions.

Registration Status

DSL: pending; AICS: pending; ENCS: pending; ICSR: pending; TSCA: pending; IECSC: pending; INSQR: pending; REACH: pending; K-REACH: pending; SEA_Regulatory: pending

Registration values are catalog reference status cues and may require jurisdiction-specific review.

Shipment review

Shipment details require review before fulfillment.

Preliminary catalog cue; verify before compliance decisions.

  • Transport classification must be confirmed using supplier SDS and shipment documentation before dispatch.