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2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-5-(trifluoromethyl)pyridine

CAS 1128269-66-8Formula C12H14BF4NO2MW 291.05PubChem 67159100

This compound is a fluorinated pyridine derivative featuring a trifluoromethyl group and a pinacol boronate ester. It serves as a versatile building block in organic synthesis, particularly for creating complex fluorinated molecules for research-use applications.

Loading RDKit molecule structure...
InChIKey: CVCZGFALKKFEQE-UHFFFAOYSA-NC12H14BF4NO2 | MW 291.05

Chemical Identity

Molecular Formula

C12H14BF4NO2

Molecular Weight

291.05 g/mol

Exact Mass

291.105372

PubChem CID

67159100

SMILES String

CC1(C)OB(c2cc(C(F)(F)F)cnc2F)OC1(C)C

Names & Synonyms

2-FLUORO-5-(TRIFLUOROMETHYL)-PYRIDINE-3-BORONIC ACID PINACOL ESTERG71316Z20497516792-fluoro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridine
External Identifiers
MFCD13182152SCHEMBL1780770MB12953EN300-12593599

Catalog Overview

2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-5-(trifluoromethyl)pyridine, identified by CAS 1128269-66-8, is a sophisticated organic compound with the molecular formula C12H14BF4NO2 and a molecular weight of 291.05. It incorporates a pyridine core substituted with a fluorine atom, a trifluoromethyl group, and a 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl (pinacol boronate) moiety. This structure makes it a valuable functionalized intermediate for advanced synthetic chemistry, enabling the introduction of both fluorine and trifluoromethyl groups, as well as facilitating cross-coupling reactions via the boronate ester.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

white to off-white solid

Physical State

solid

Melting Point

95.0 °C

Boiling Point

280.0 °C

Density

1.4 g/cm³

Water Solubility

insoluble

Flash Point

145.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information before use.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Related CAS / Similar Products

2-Fluoro-6-(trifluoromethyl)pyridine-4-boronic acid pinacol esterCAS 1169459-44-23-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridineCAS 1984826-57-46-Fluoro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridineCAS 2710289-82-82-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridineCAS 1971914-58-5

Similar products (text references)

2710289-79-3CAS 2710289-79-3

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 293339GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Related catalog entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1971914-58-52-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridineCAS 1984826-57-43-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridineCAS 2710289-82-86-Fluoro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridineCAS 1169459-44-22-Fluoro-6-(trifluoromethyl)pyridine-4-boronic acid pinacol esterCAS 2223041-77-62-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyridineCAS 2223054-08-6Pyridine, 3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-CAS 1321518-03-92-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridineCAS 1356579-72-02-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridine