Chemical Identity
Molecular Formula
C12H15BF3NO2
Molecular Weight
273.06 g/mol
Exact Mass
273.114793
PubChem CID
49760460
IUPAC Name
4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine
SMILES String
CC1(C)OB(c2ccncc2C(F)(F)F)OC1(C)C
Names & Synonyms
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External Identifiers
Catalog Overview
4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine is an organoboron compound characterized by a pyridine ring substituted with a trifluoromethyl group at position 3 and a pinacol boronic ester at position 4. The pinacol boronic ester moiety makes it a highly reactive and valuable reagent for various carbon-carbon bond-forming reactions, such as Suzuki-Miyaura coupling, enabling the introduction of the 3-(trifluoromethyl)pyridin-4-yl group into complex molecular structures. Its trifluoromethyl group can impart unique electronic and steric properties to target molecules.
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
Colorless to pale yellow liquid
Physical State
Liquid
Melting Point
86.0 °C
Boiling Point
242.0 °C
Density
1.3 g/cm³
Water Solubility
9.33 × 10⁻⁴ mol/L
Flash Point
110.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures.
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Related CAS / Similar Products
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Recommended application cues
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Related HS Code / Compliance
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