3-Chloro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylic acid

3-Chloro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylic acid is a sophisticated organic compound with the molecular formula C12H15BClNO4 and a molecular weight of 283.52. It incorporates a pyridine core substituted with a chlorine atom, a carboxylic acid group, and a 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl (pinacol boronic ester) moiety. This unique combination of functional groups makes it a valuable intermediate in synthetic chemistry. The pinacol boronic ester is particularly useful for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds with aryl or vinyl halides. The presence of a chlorine atom and a carboxylic acid group on the pyridine ring provides additional handles for further chemical transformations, allowing for the synthesis of diverse pyridine-containing compounds. This chemical is strictly for Research Use Only (RUO).

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information before use.