1-Amino-6-(trifluoromethyl)-2,3-dihydro-1H-indene-1-carboxylic acid

This compound, 1-Amino-6-(trifluoromethyl)-2,3-dihydro-1H-indene-1-carboxylic acid, is a chiral indane derivative incorporating a trifluoromethyl group at the 6-position and an amino and carboxylic acid group at the 1-position. The trifluoromethyl group is known to impart increased lipophilicity, metabolic stability, and modulate electronic properties, making it valuable in medicinal chemistry and agrochemical research. The amino and carboxylic acid functionalities provide reactive sites for various synthetic transformations, including amide bond formation, esterification, and salt formation, enabling its use in the construction of diverse chemical scaffolds.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Always follow standard laboratory safety procedures and consult the Safety Data Sheet (SDS) for detailed handling and storage information. For research use only.