Active Chemical RecordCatalog PreviewCatalog ready

7-Methyl-6-(trifluoromethyl)-1H-indole-2-carboxylic acid

CAS 2060039-09-8Formula C11H8F3NO2MW 243.18PubChem 125456284

This compound is a trifluoromethyl-substituted indole derivative, featuring a carboxylic acid group. It is primarily used as a versatile building block in organic synthesis, particularly for creating more complex indole-containing structures for research purposes.

Loading RDKit molecule structure...
InChIKey: GTWOOHMYRZQWQS-UHFFFAOYSA-NC11H8F3NO2 | MW 243.18

Chemical Identity

Molecular Formula

C11H8F3NO2

Molecular Weight

243.18 g/mol

Exact Mass

243.050713

PubChem CID

125456284

SMILES String

Cc1c(C(F)(F)F)ccc2cc(C(=O)O)[nH]c12

Names & Synonyms

7-Methyl-6-(trifluoromethyl)-1H-indole-2-carboxylicacid
External Identifiers
AT51376EN300-340411

Catalog Overview

7-Methyl-6-(trifluoromethyl)-1H-indole-2-carboxylic acid is an organic compound characterized by an indole core substituted with a methyl group at position 7, a trifluoromethyl group at position 6, and a carboxylic acid group at position 2. With a molecular formula of C11H8F3NO2 and a molecular weight of 243.18 g/mol, this compound presents a unique combination of electron-withdrawing (trifluoromethyl) and electron-donating (methyl) groups on the indole ring, alongside a reactive carboxylic acid functionality. These features make it a valuable intermediate in the synthesis of various indole-based compounds, which are often...

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

7-Methyl-6-(trifluoromethyl)-1H-indole-2-carboxylic acid is an organic compound characterized by an indole core substituted with a methyl group at position 7, a trifluoromethyl group at position 6, and a carboxylic acid group at position 2. With a molecular formula of C11H8F3NO2 and a molecular weight of 243.18 g/mol, this compound presents a unique combination of electron-withdrawing (trifluoromethyl) and electron-donating (methyl) groups on the indole ring, alongside a reactive carboxylic acid functionality. These features make it a valuable intermediate in the synthesis of various indole-based compounds, which are often explored in medicinal chemistry and materials science. It is intended for research use only.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White to off-white crystalline powder

Physical State

Solid

Melting Point

200.0 °C

Boiling Point

400.0 °C

Density

1.45 g/cm³

Water Solubility

Slightly soluble

Flash Point

250.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle 7-Methyl-6-(trifluoromethyl)-1H-indole-2-carboxylic acid with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Always refer to the Safety Data Sheet (SDS) for comprehensive safety information before handling. This product is for research use only and not for human or animal consumption.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

2305253-74-9CAS 2305253-74-9
1806276-23-2CAS 1806276-23-2
208517-34-4CAS 208517-34-4

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 293399GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.