Chemical Identity
Molecular Formula
C12H15BF3NO2
Molecular Weight
273.06 g/mol
Exact Mass
273.114793
PubChem CID
53398060
SMILES String
CC1(C)OB(c2cnccc2C(F)(F)F)OC1(C)C
Names & Synonyms
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External Identifiers
Catalog Overview
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyridine is a highly functionalized organic compound. It incorporates a pyridine ring substituted with a trifluoromethyl group at the 4-position and a pinacol boronic ester at the 3-position. The trifluoromethyl group is known for its electron-withdrawing properties and metabolic stability, while the pinacol boronic ester is a versatile moiety commonly employed in Suzuki-Miyaura cross-coupling reactions. This combination makes the compound a key intermediate for synthesizing complex molecules with potential applications in medicinal chemistry and materials science....
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyridine is a highly functionalized organic compound. It incorporates a pyridine ring substituted with a trifluoromethyl group at the 4-position and a pinacol boronic ester at the 3-position. The trifluoromethyl group is known for its electron-withdrawing properties and metabolic stability, while the pinacol boronic ester is a versatile moiety commonly employed in Suzuki-Miyaura cross-coupling reactions. This combination makes the compound a key intermediate for synthesizing complex molecules with potential applications in medicinal chemistry and materials science. It is intended for research use only.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
white solid
Physical State
solid
Melting Point
86.0 °C
Boiling Point
242.0 °C
Density
1.3 g/cm³
Water Solubility
9.33 × 10⁻⁴ mol/L
Flash Point
135.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood. Avoid inhalation, ingestion, and skin contact. Refer to the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. Store in a cool, dry place, away from incompatible materials.
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