Chemical Identity
Molecular Formula
C12H14BF4NO2
Molecular Weight
291.05 g/mol
Exact Mass
291.105372
PubChem CID
53417043
IUPAC Name
2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine
SMILES String
CC1(C)OB(c2cc(F)nc(C(F)(F)F)c2)OC1(C)C
Names & Synonyms
External Identifiers
Catalog Overview
2-Fluoro-6-(trifluoromethyl)pyridine-4-boronic acid pinacol ester is a highly functionalized pyridine derivative. It incorporates a fluorine atom and a trifluoromethyl group on the pyridine ring, along with a pinacol boronic ester moiety at the 4-position. This combination of functional groups makes it a valuable intermediate in the synthesis of complex organic molecules, especially in medicinal chemistry and materials science. The boronic ester group allows for facile C-C bond formation through Suzuki-Miyaura coupling, while the fluorine and trifluoromethyl groups can impart specific electronic and steric properties to the final...
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
2-Fluoro-6-(trifluoromethyl)pyridine-4-boronic acid pinacol ester is a highly functionalized pyridine derivative. It incorporates a fluorine atom and a trifluoromethyl group on the pyridine ring, along with a pinacol boronic ester moiety at the 4-position. This combination of functional groups makes it a valuable intermediate in the synthesis of complex organic molecules, especially in medicinal chemistry and materials science. The boronic ester group allows for facile C-C bond formation through Suzuki-Miyaura coupling, while the fluorine and trifluoromethyl groups can impart specific electronic and steric properties to the final compounds.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
white crystalline solid
Physical State
solid
Melting Point
97.0 °C
Boiling Point
242.0 °C
Density
1.5 g/cm³
Water Solubility
5.89 × 10⁻⁴ mol/L
Flash Point
120.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Refer to the Safety Data Sheet (SDS) for comprehensive safety information. This product is for research use only and not for human or animal therapeutic or diagnostic use.
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
Related CAS / Similar Products
Similar products (text references)
Recommended application cues
Catalog discovery cues, not supplier-verified claims.
Related HS Code / Compliance
Compliance cues are non-linked reference tags and require shipment review.