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2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine

CAS 2068737-11-9Formula C12H14BClF3NO2MW 307.5PubChem 72221287

2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine is a functionalized pyridine derivative featuring a chloro group, a trifluoromethyl group, and a pinacol boronic ester. This compound serves as a versatile building block in organic synthesis, particularly for cross-coupling reactions.

Loading RDKit molecule structure...
InChIKey: JGYNUOKLWMKKRA-UHFFFAOYSA-NC12H14BClF3NO2 | MW 307.5

Chemical Identity

Molecular Formula

C12H14BClF3NO2

Molecular Weight

307.5 g/mol

Exact Mass

307.075821

PubChem CID

72221287

SMILES String

CC1(C)OB(c2ccc(C(F)(F)F)nc2Cl)OC1(C)C

Names & Synonyms

971-407-72-Chloro-6-trifluoromethylpyridine-3-boronic acid pinacol ester2-Chloro-6-trifluoromethylpyridin-3-bronic acid, pinacol ester2-CHLORO-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-6-(TRIFLUOROMETH+JGYNUOKLWMKKRA-UHFFFAOYSA-N
Show all synonyms
2-Chloro-6-trifluoromethylpyridin-3-boronic acid pinacol esterF621414Z20497576732-chloro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine
External Identifiers
RefChem:468618MFCD16996474SCHEMBL18030715THD73711AT14250MB20850BS-33967CS-0136592EN300-1662378

Catalog Overview

2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine, with CAS 2068737-11-9, is a valuable research chemical characterized by a pyridine core substituted with a chlorine atom, a trifluoromethyl group, and a pinacol boronic ester. The presence of the boronic ester makes it an excellent reagent for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The chloro and trifluoromethyl groups provide opportunities for further functionalization or introduce specific electronic and steric properties, making this compound a key intermediate in the synthesis of complex...

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine, with CAS 2068737-11-9, is a valuable research chemical characterized by a pyridine core substituted with a chlorine atom, a trifluoromethyl group, and a pinacol boronic ester. The presence of the boronic ester makes it an excellent reagent for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The chloro and trifluoromethyl groups provide opportunities for further functionalization or introduce specific electronic and steric properties, making this compound a key intermediate in the synthesis of complex organic molecules, including potential pharmaceutical and agrochemical candidates, for research purposes only.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White to off-white crystalline powder

Physical State

Solid

Melting Point

85.0 °C

Boiling Point

280.0 °C

Density

1.4 g/cm³

Water Solubility

Slightly soluble

Flash Point

135.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle 2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or a chemical fume hood to avoid inhalation. Prevent skin and eye contact, and do not ingest. Always consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. Store in a cool, dry place away from incompatible materials.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 293339GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.