Chemical Identity
Molecular Formula
C12H14BClF3NO2
Molecular Weight
307.5 g/mol
Exact Mass
307.075821
PubChem CID
66666577
SMILES String
CC1(C)OB(c2cnc(C(F)(F)F)c(Cl)c2)OC1(C)C
Names & Synonyms
External Identifiers
Catalog Overview
3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine, with CAS 1355067-84-3, is a sophisticated organoboron compound. Its structure combines a chlorinated and trifluoromethylated pyridine ring with a pinacol boronate ester. This unique combination makes it a highly valuable intermediate in synthetic chemistry, enabling the formation of new carbon-carbon bonds through palladium-catalyzed cross-coupling reactions. The trifluoromethyl group often imparts specific electronic and steric properties, while the chlorine atom provides another site for further functionalization, making it a versatile building...
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine, with CAS 1355067-84-3, is a sophisticated organoboron compound. Its structure combines a chlorinated and trifluoromethylated pyridine ring with a pinacol boronate ester. This unique combination makes it a highly valuable intermediate in synthetic chemistry, enabling the formation of new carbon-carbon bonds through palladium-catalyzed cross-coupling reactions. The trifluoromethyl group often imparts specific electronic and steric properties, while the chlorine atom provides another site for further functionalization, making it a versatile building block for complex molecular architectures in research settings.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
white to off-white crystalline powder
Physical State
solid
Melting Point
100.0 °C
Boiling Point
350.0 °C
Density
1.4 g/cm³
Water Solubility
insoluble or sparingly soluble
Flash Point
160.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment (PPE), including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for comprehensive safety information before use. This product is for research use only and not for human or animal therapeutic or diagnostic use.
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
Related products and analog discovery will be available as catalog graph data is expanded.