Chemical Identity
Molecular Formula
C6H4BF4NO2
Molecular Weight
208.91 g/mol
Exact Mass
209.027121
PubChem CID
91882927
IUPAC Name
[6-fluoro-2-(trifluoromethyl)-3-pyridinyl]boronic acid
SMILES String
OB(O)c1ccc(F)nc1C(F)(F)F
Names & Synonyms
Show all synonyms
External Identifiers
Catalog Overview
[6-Fluoro-2-(trifluoromethyl)pyridin-3-yl]boronic acid is a valuable research-use chemical characterized by a pyridine ring substituted with a fluorine atom, a trifluoromethyl group, and a boronic acid moiety. The presence of both fluorine and trifluoromethyl groups can impart unique electronic and steric properties, influencing reactivity and biological activity in derived molecules. The boronic acid functionality is highly reactive, making it an excellent precursor for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds with aryl or vinyl halides. It is widely utilized in the synthesis of...
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
[6-Fluoro-2-(trifluoromethyl)pyridin-3-yl]boronic acid is a valuable research-use chemical characterized by a pyridine ring substituted with a fluorine atom, a trifluoromethyl group, and a boronic acid moiety. The presence of both fluorine and trifluoromethyl groups can impart unique electronic and steric properties, influencing reactivity and biological activity in derived molecules. The boronic acid functionality is highly reactive, making it an excellent precursor for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds with aryl or vinyl halides. It is widely utilized in the synthesis of complex organic molecules, including potential pharmaceutical intermediates and agrochemicals, where precise structural modifications are crucial.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White to off-white powder or crystalline solid
Physical State
Solid
Melting Point
145.0 °C
Boiling Point
310.0 °C
Density
1.5 g/cm³
Water Solubility
Slightly soluble
Flash Point
180.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle [6-Fluoro-2-(trifluoromethyl)pyridin-3-yl]boronic acid in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Avoid inhalation of dust or vapors and direct contact with skin and eyes. In case of contact, rinse thoroughly with water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for comprehensive safety information before use.
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
Related CAS / Similar Products
Similar products (text references)
Recommended application cues
Catalog discovery cues, not supplier-verified claims.
Related HS Code / Compliance
Compliance cues are non-linked reference tags and require shipment review.