Active Chemical RecordCatalog PreviewCatalog ready

3-Fluoro-2-(trifluoromethyl)pyridine-4-boronic acid

CAS 2096337-73-2Formula C6H4BF4NO2MW 208.91PubChem 121237361

This compound is a fluorinated pyridine boronic acid derivative, commonly used as a versatile building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions. It is valuable for introducing a 3-fluoro-2-(trifluoromethyl)pyridine moiety into target molecules for research purposes.

Loading RDKit molecule structure...
InChIKey: WNZKMQKVWZYROZ-UHFFFAOYSA-NC6H4BF4NO2 | MW 208.91

Chemical Identity

Molecular Formula

C6H4BF4NO2

Molecular Weight

208.91 g/mol

Exact Mass

209.027121

PubChem CID

121237361

IUPAC Name

[3-fluoro-2-(trifluoromethyl)-4-pyridinyl]boronic acid

SMILES String

OB(O)c1ccnc(C(F)(F)F)c1F

Names & Synonyms

[3-fluoro-2-(trifluoromethyl)pyridin-4-yl]boronic acidBoronic acid, B-[3-fluoro-2-(trifluoromethyl)-4-pyridinyl]-(3-Fluoro-2-(trifluoromethyl)pyridin-4-yl)boronic acid[3-fluoro-2-(trifluoromethyl)-4-pyridyl]boronic acid
External Identifiers
MFCD16611330SCHEMBL25707523SCHEMBL29955831DTXSID201190987EN300-8688428

Catalog Overview

3-Fluoro-2-(trifluoromethyl)pyridine-4-boronic acid (CAS 2096337-73-2) is a highly functionalized pyridine derivative featuring both a fluorine atom and a trifluoromethyl group on the pyridine ring, along with a boronic acid functional group at the 4-position. With a molecular formula of C6H4BF4NO2 and a molecular weight of 208.91, this compound serves as a key intermediate in the synthesis of complex organic molecules. The boronic acid group makes it particularly suitable for palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds with diverse aryl or...

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

3-Fluoro-2-(trifluoromethyl)pyridine-4-boronic acid (CAS 2096337-73-2) is a highly functionalized pyridine derivative featuring both a fluorine atom and a trifluoromethyl group on the pyridine ring, along with a boronic acid functional group at the 4-position. With a molecular formula of C6H4BF4NO2 and a molecular weight of 208.91, this compound serves as a key intermediate in the synthesis of complex organic molecules. The boronic acid group makes it particularly suitable for palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds with diverse aryl or heteroaryl halides. The presence of fluorine and trifluoromethyl groups can impart unique electronic and steric properties to synthesized compounds, making this boronic acid valuable in medicinal chemistry and materials science research for developing novel compounds with enhanced biological activity or specific material properties. It is intended for Research Use Only (RUO).

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White crystalline powder

Physical State

Solid

Melting Point

209.0 °C

Boiling Point

317.0 °C

Density

1.55 g/cm³

Water Solubility

0.214 mol/L

Flash Point

170.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. This product is for Research Use Only.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Related products and analog discovery will be available as catalog graph data is expanded.