Chemical Identity
Molecular Formula
C6H4BF4NO2
Molecular Weight
208.91 g/mol
Exact Mass
209.027121
PubChem CID
91882757
IUPAC Name
[6-fluoro-5-(trifluoromethyl)-3-pyridinyl]boronic acid
SMILES String
OB(O)c1cnc(F)c(C(F)(F)F)c1
Names & Synonyms
External Identifiers
Catalog Overview
This compound is a highly functionalized boronic acid, incorporating a pyridine ring substituted with both a fluorine atom and a trifluoromethyl group. The boronic acid moiety enables its use in various palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, for the efficient formation of carbon-carbon bonds. The presence of fluorine and trifluoromethyl groups can impart unique electronic, steric, and physicochemical properties to target molecules, making this intermediate particularly useful in the synthesis of novel pharmaceuticals, agrochemicals, and advanced materials for research purposes. It serves...
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- Research chemical sourcing
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Read more catalog context
This compound is a highly functionalized boronic acid, incorporating a pyridine ring substituted with both a fluorine atom and a trifluoromethyl group. The boronic acid moiety enables its use in various palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, for the efficient formation of carbon-carbon bonds. The presence of fluorine and trifluoromethyl groups can impart unique electronic, steric, and physicochemical properties to target molecules, making this intermediate particularly useful in the synthesis of novel pharmaceuticals, agrochemicals, and advanced materials for research purposes. It serves as a versatile tool for introducing complex fluorinated pyridine scaffolds into diverse chemical structures.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White to off-white powder
Physical State
Solid
Melting Point
145.0 °C
Boiling Point
280.0 °C
Density
1.5 g/cm³
Water Solubility
Slightly soluble
Flash Point
180.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Prevent skin and eye contact. Do not ingest. Store in a cool, dry place, away from incompatible materials. In case of exposure, seek immediate medical attention. Always refer to the Safety Data Sheet (SDS) for comprehensive safety information.
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
Related products and analog discovery will be available as catalog graph data is expanded.