4-Chloro-2-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

4-Chloro-2-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile, identified by CAS 2223054-28-0, is a meticulously synthesized organic compound featuring a chlorinated, methylated, and cyanated benzene ring substituted with a pinacol boronate group. With a molecular formula of C14H17BClNO2 and a molecular weight of 277.55, this compound serves as a key functionalized intermediate. Its boronic ester functionality makes it highly reactive in palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, facilitating the introduction of aryl groups into various synthetic pathways. The presence of a nitrile group and a chlorine atom provides additional sites for further chemical transformations, making it a versatile reagent for constructing diverse chemical structures in academic and industrial research settings.

• Handle 4-Chloro-2-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Refer to the Safety Data Sheet (SDS) for comprehensive safety information before use.