Research chemical
CAS Number: 2225151-82-4
Product details
For laboratory research and professional procurement workflows.
PubChem CID
133555288
Exact Mass
273.114793
InChIKey
SJLKIWHQTAIGIZ-UHFFFAOYSA-N
IUPAC Name
[2-piperidin-3-yl-4-(trifluoromethyl)phenyl]boronic acid
SMILES String
OB(O)c1ccc(C(F)(F)F)cc1C1CCCNC1
Appearance
Catalog navigation
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2-(Piperidin-3-yl)-4-trifluoromethylphenylboronic acid is identified by CAS 2225151-82-4, with molecular formula C12H15BF3NO2, molecular weight 273.06, InChIKey SJLKIWHQTAIGIZ-UHFFFAOYSA-N.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.
White to off-white crystalline powder
Physical State
Solid
Melting Point
155.0 °C
Density
1.3 g/cm³
Water Solubility
Slightly soluble
Flash Point
250.0 °C
Vapor Pressure
Estimated very low; unit not specified
Autoignition Temp
400.0 °C
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Heavy atom count
19
H-bond acceptors
3
H-bond donors
3
Rotatable bonds
2
Ring count
2
Aromatic rings
1
Topological polar surface area
52.49 Ų
Computed LogP
0.85
Fragment-like structure rule
Yes
Lead-like structure rule
Yes
Drug-like structure rule
Yes
Structure family
n heterocycle ligand
Precious metal motif
No
Transition metal motif
No
Phosphine ligand motif
No
N-heterocycle motif
Yes
Boronic acid motif
Yes
Computed structure descriptors generated from molecular structure. These are not experimental physical property values, supplier specifications, SDS data, or bioactivity claims.
Structural features
2-(Piperidin-3-yl)-4-trifluoromethylphenylboronic acid is a functionalized boronic acid derivative featuring a trifluoromethylphenyl group and a piperidinyl substituent.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Primarily utilized as a versatile building block in organic synthesis, especially for Suzuki-Miyaura cross-coupling reactions to form new carbon-carbon bonds.
Documentation needs
Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes.
For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.
Preliminary Safety Reference
For supplier-issued SDS or COA, submit a documentation request.
Safety Reference / SDS Request