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Home/Compounds/CAS 100-33-4
Formula C19H24N4O2MW 340.4Research-use catalog entryCOA/SDS by request

Pentamidine

CAS Number: 100-33-4

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Available Options

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1 g
Purity
99%
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100 mg
Purity
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250 mg
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50 mg
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Loading RDKit molecule structure...
InChIKey: XDRYMKDFEDOLFX-UHFFFAOYSA-NC19H24N4O2 | MW 340.4

Chemical Absolute Identifiers

CAS Number

100-33-4

PubChem CID

4735

Molecular Formula

C19H24N4O2

Molecular Weight

340.4 g/mol

Exact Mass

340.189926

InChIKey

XDRYMKDFEDOLFX-UHFFFAOYSA-N

IUPAC Name

4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide

SMILES String

C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Pentamidine (CAS 100-33-4) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C19H24N4O2 and molecular weight 340. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Protein tyrosine phosphatase type IVA 3 (Homo sapiens) — 3 assays; Multidrug and toxin extrusion protein 1 (Homo sapiens) — 6 assays; Alpha-2A adrenergic receptor (Homo sapiens) — 2 assays; Muscarinic acetylcholine receptor M2 (Homo sapiens) — 2 assays; Amine oxidase [flavin-containing] A (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Protein tyrosine phosphatase type IVA 3

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 6.52

Experimental evidence source: ChEMBL

Multidrug and toxin extrusion protein 1

Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 2 documents · best pChEMBL 6.39

Experimental evidence source: ChEMBL

Alpha-2A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.29

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.29

Experimental evidence source: ChEMBL

Amine oxidase [flavin-containing] A

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.1

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • The product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Pentamidine

Names & Synonyms

Pentamidina4,4'-(Pentamethylenedioxy)dibenzamidinePentamidinPentamidinum4,4'-Diamidinodiphenoxypentane
Show all synonyms
p,p'-(Pentamethylenedioxy)dibenzamidinePentam 300 (as isethionate)Nebupent (as isethionate)Pentacarinat (as isethionate)Benzenecarboximidamide, 4,4'-[1,5-pentanediylbis(oxy)]bis-1,5-bis(4-amidinophenoxy)pentaneMB 800 FREE BASEMB-800 FREE BASE4,4'-(1,5-Pentanediylbis(oxy))bis-benzenecarboximidamideRP 2512 FREE BASERP-2512 FREE BASE4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}benzene-1-carboximidamideMB-800 (AS ISETHIONATE)4,4'-[1,5-Pentanediylbis(oxy)]bis-benzenecarboximidamideBenzenecarboximidamide, 4,4'-(1,5-pentanediylbis(oxy))bis-
External Identifiers
EC NUMBER: 202-841-0DSSTOX SUBSTANCE ID: DTXSID7023431CHEMBL ID: CHEMBL55CHEBI ID: CHEBI:45081UNII: 673LC5J4LQDRUGBANK ID: DB00738HMDB ID: HMDB0014876KEGG ID: C07420KEGG ID: D08333METABOLOMICS WORKBENCH ID: 43042NCI THESAURUS CODE: C731PHARMGKB ID: PA450850RXCUI: 7994WIKIDATA ID: Q416206
Literature & Patent References
DOI 10.1016/j.ejmech.2024.117109Nanomolar activity of coumarin-3-thiosemicarbazones targeting Trypanosoma cruzi cruzain and the T. brucei cathepsin L-like protease.DOI 10.1016/j.ejmech.2025.117478Exploring chloro-isoxazole compounds inspired on tetrahydrofuran neolignans as promising antileishmanial agents.DOI 10.1021/acs.jmedchem.5c00056Substrate Specificity of the Organic Cation Transporters MATE1 and MATE2K and Functional Overlap with OCT1 and OCT2.DOI 10.1021/acs.jnatprod.4c00834Cyclic Peptide Natural Product Inspired Inhibitors of the Free-Living Amoeba <i>Balamuthia mandrillaris</i>.DOI 10.1021/acs.jnatprod.5c00141Sealgamide: An Antitrypanosomal Lipopeptide Isolated from a Marine <i>Okeania</i> sp. Cyanobacterium.PMID 39653622Nanomolar activity of coumarin-3-thiosemicarbazones targeting Trypanosoma cruzi cruzain and the T. brucei cathepsin L-like protease.PMID 39948695Cyclic Peptide Natural Product Inspired Inhibitors of the Free-Living Amoeba <i>Balamuthia mandrillaris</i>.PMID 40112663Exploring chloro-isoxazole compounds inspired on tetrahydrofuran neolignans as promising antileishmanial agents.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

Pentamidine dihydrochlorideCAS 50357-45-4
BepheniumCAS 7181-73-9
PafuramidineCAS 186953-56-0
OxibendazoleCAS 20559-55-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 50357-45-4Pentamidine dihydrochlorideCAS 111-24-01,5-DibromopentaneCAS 21829-25-4NifedipineCAS 23593-75-1ClotrimazoleCAS 63612-50-0NilutamideCAS 58-14-0PyrimethamineCAS 76824-35-6FamotidineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 100-33-4

What are the key identifiers for Pentamidine (CAS 100-33-4)?

Pentamidine is identified by CAS 100-33-4, with molecular formula C19H24N4O2, molecular weight 340.4, InChIKey XDRYMKDFEDOLFX-UHFFFAOYSA-N.

Does CAS 100-33-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Protein tyrosine phosphatase type IVA 3, Multidrug and toxin extrusion protein 1, Alpha-2A adrenergic receptor, Muscarinic acetylcholine receptor M2, Amine oxidase [flavin-containing] A. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 100-33-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Pentamidine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 100-33-4 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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