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Home/Compounds/CAS 1000787-75-6
Formula C25H14F7N5MW 517.4Research-use catalog entryCOA/SDS by request

Tegobuvir

CAS Number: 1000787-75-6

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Loading RDKit molecule structure...
InChIKey: XBEQSQDCBSKCHJ-UHFFFAOYSA-NC25H14F7N5 | MW 517.4

Chemical Absolute Identifiers

CAS Number

1000787-75-6

PubChem CID

23649154

Molecular Formula

C25H14F7N5

Molecular Weight

517.4 g/mol

Exact Mass

517.113743

InChIKey

XBEQSQDCBSKCHJ-UHFFFAOYSA-N

IUPAC Name

5-[[6-[2,4-bis(trifluoromethyl)phenyl]pyridazin-3-yl]methyl]-2-(2-fluorophenyl)imidazo[4,5-c]pyridine

SMILES String

Fc1ccccc1-c1nc2ccn(Cc3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)nn3)cc-2n1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Tegobuvir (CAS 1000787-75-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C25H14F7N5 and molecular weight 517. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: RNA-directed RNA polymerase (Hepacivirus hominis) — 2 assays; Voltage-gated inwardly rectifying potassium channel KCNH2 (Homo sapiens) — 2 assays; Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

RNA-directed RNA polymerase

Hepacivirus hominis · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 8.54

Experimental evidence source: ChEMBL

Voltage-gated inwardly rectifying potassium channel KCNH2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.1

Experimental evidence source: ChEMBL

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Tegobuvir

Names & Synonyms

5-((6-(2,4-bis(Trifluoromethyl)phenyl)pyridazin-3-yl)methyl)-2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine5-({6-[2,4-bis(trifluoromethyl)phenyl]pyridazin-3-yl}methyl)-2-(2-fluorophenyl)-5h-imidazo[4,5-c]pyridinetegobuvirum5-((6-(2,4-BIS(TRIFLUOROMETHYL)PHENYL)PYRIDAZIN-3-YL)METHYL)-2-(2-FLUOROPHENYL)-5H-IMIDAZO(4,5-C)PYRIDINE5-((6-(2,4-bis(trifluoromethyl)phenyl)pyridazin-3-yl)methyl)-2-(2-fluorophenyl)imidazo(4,5-c)pyridine
Show all synonyms
3-[2,4-bis(trifluoromethyl)phenyl]-6-{[2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridin-5-yl]methyl}pyridazineTegobuvir [USAN:INN]Tegobuvir [INN]GS 9190GS 333126Tegobuvir (USAN/INN)TEGOBUVIR [USAN]TEGOBUVIR [WHO-DD]5H-IMIDAZO(4,5-C)PYRIDINE, 5-((6-(2,4-BIS(TRIFLUOROMETHYL)PHENYL)-3-PYRIDAZINYL)METHYL)- 2-(2-FLUOROPHENYL)-5H-Imidazo[4,5-c]pyridine, 5-[[6-[2,4-bis(trifluoromethyl)phenyl]-3-pyridazinyl]methyl]-2-(2-fluorophenyl)-
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID80142917CHEMBL ID: CHEMBL1957287UNII: 5NOK5X389MDRUGBANK ID: DB11852KEGG ID: D09971METABOLOMICS WORKBENCH ID: 144555NCI THESAURUS CODE: C152541WIKIDATA ID: Q27262603
Literature & Patent References
DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1016/j.bmc.2018.04.029Design, synthesis, and structure-activity relationships of novel imidazo[4,5-c]pyridine derivatives as potent non-nucleoside inhibitors of hepatitis C virus NS5B.PMID 29681484Design, synthesis, and structure-activity relationships of novel imidazo[4,5-c]pyridine derivatives as potent non-nucleoside inhibitors of hepatitis C virus NS5B.DOI 10.1021/jm401337xImidazopyridazine hepatitis C virus polymerase inhibitors. Structure-activity relationship studies and the discovery of a novel, traceless prodrug mechanism.PMID 24224729Imidazopyridazine hepatitis C virus polymerase inhibitors. Structure-activity relationship studies and the discovery of a novel, traceless prodrug mechanism.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

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RFQ questions for CAS 1000787-75-6

What are the key identifiers for Tegobuvir (CAS 1000787-75-6)?

Tegobuvir is identified by CAS 1000787-75-6, with molecular formula C25H14F7N5, molecular weight 517.4, InChIKey XBEQSQDCBSKCHJ-UHFFFAOYSA-N.

Does CAS 1000787-75-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with RNA-directed RNA polymerase, Voltage-gated inwardly rectifying potassium channel KCNH2, Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1000787-75-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Tegobuvir?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 1000787-75-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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