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Home/Compounds/CAS 101827-46-7
Formula C23H28ClNMW 353.9Research-use catalog entryCOA/SDS by request

Butenafine Hydrochloride

CAS Number: 101827-46-7

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Available Options

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1 g
Purity
98%
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1 mg
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25 g
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5 g
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Loading RDKit molecule structure...
InChIKey: LJBSAUIFGPSHCN-UHFFFAOYSA-NC23H28ClN | MW 353.9

Chemical Absolute Identifiers

CAS Number

101827-46-7

PubChem CID

443867

Molecular Formula

C23H28ClN

Molecular Weight

353.9 g/mol

Exact Mass

353.191028

InChIKey

LJBSAUIFGPSHCN-UHFFFAOYSA-N

IUPAC Name

1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine;hydrochloride

SMILES String

CC(C)(C)C1=CC=C(C=C1)CN(C)CC2=CC=CC3=CC=CC=C32.Cl

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Butenafine Hydrochloride (CAS 101827-46-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C23H28ClN and molecular weight 353. 90 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Replicase polyprotein 1ab (Severe acute respiratory syndrome coronavirus 2) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Replicase polyprotein 1ab

Severe acute respiratory syndrome coronavirus 2 · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 5.27

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Butenafine Hydrochloride

Names & Synonyms

Butenafine HCLMentaxN-(p-tert-Butylbenzyl)-N-methyl-1-naphthalenemethylamine hydrochlorideVolleyMentax-TC
Show all synonyms
N-4-tert-Butylbenzyl-N-methyl-1-naphthalenemethylamine hydrochloride1-Naphthalenemethanamine, N-((4-(1,1-dimethylethyl)phenyl)methyl)-N-methyl-, hydrochlorideN-((4-(1,1-Dimethylethyl)phenyl)methyl)-N-methyl-1-naphthalenemethanamine hydrochlorideN-[[4-(1,1-Dimethylethyl)phenyl]methyl]-N-methyl-1-naphthalenemethanamine hydrochlorideLotrimin UltraJock Itch CreamAthletes Foot UltraLotrimin Ultra RingwormAntifungal Foot TreatmentLotrimin Ultra Jock ItchButenafine Hydrochloride 1%Lotrimin Ultra Athletes FootButenafine Hydrochloride Jock ItchButenafine Hydrochloride Athletes FootN-4-tert-butylbenzyl-N-methyl-1-naphthalene methylamine hydrochloride
External Identifiers
EC NUMBER: 642-354-4DSSTOX SUBSTANCE ID: DTXSID2048589CHEMBL ID: CHEMBL1200397CHEBI ID: CHEBI:31325UNII: R8XA2029ZIKEGG ID: C12490KEGG ID: D01093METABOLOMICS WORKBENCH ID: 69910NCI THESAURUS CODE: C47426RXCUI: 236558
Experimental Spectrum References
ATR-IR Spectra — Bio-Rad Laboratories, Inc.FTIR Spectra — Bio-Rad Laboratories, Inc.Raman Spectra — Bio-Rad Laboratories, Inc.
Literature & Patent References
DOI 10.1016/j.ejmech.2023.115491The research progress of SARS-CoV-2 main protease inhibitors from 2020 to 2022.PMID 37244162The research progress of SARS-CoV-2 main protease inhibitors from 2020 to 2022.DOI 10.1101/2020.04.03.023846In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replicationDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.6019/CHEMBL4513161CO-ADD screening of MMV (CH) - Pandemic Response Box

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Terbinafine HydrochlorideCAS 78628-80-5
TerbinafineCAS 91161-71-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 78628-80-5Terbinafine HydrochlorideCAS 91161-71-6TerbinafineCAS 22204-53-1NaproxenCAS 60940-34-3EbselenCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 101827-46-7

What are the key identifiers for Butenafine Hydrochloride (CAS 101827-46-7)?

Butenafine Hydrochloride is identified by CAS 101827-46-7, with molecular formula C23H28ClN, molecular weight 353.9, InChIKey LJBSAUIFGPSHCN-UHFFFAOYSA-N.

Does CAS 101827-46-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Replicase polyprotein 1ab. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 101827-46-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Butenafine Hydrochloride?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 101827-46-7 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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