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- 1 g
- Purity
- 98%
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CAS Number: 1032900-25-6
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CAS Number
1032900-25-6
PubChem CID
57379345
Molecular Formula
C28H36ClN5O3S
Molecular Weight
558.1 g/mol
Exact Mass
557.222739
InChIKey
VERWOWGGCGHDQE-UHFFFAOYSA-N
IUPAC Name
5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine
SMILES String
Cc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC(C)C)cc1C1CCNCC1
pKa
9.7
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Ceritinib (CAS 1032900-25-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C28H36ClN5O3S and molecular weight 558. 10 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: ALK tyrosine kinase receptor (Homo sapiens) — 91 assays; Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens) — 16 assays; Insulin receptor (Homo sapiens) — 7 assays; Insulin-like growth factor 1 receptor (Homo sapiens) — 4 assays; Epidermal growth factor receptor (Homo sapiens) — 22 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
ALK tyrosine kinase receptor
Homo sapiens · SINGLE PROTEIN · 91 qualifying assays · 37 documents · best pChEMBL 9.7
Experimental evidence source: ChEMBL
Proto-oncogene tyrosine-protein kinase ROS
Homo sapiens · SINGLE PROTEIN · 16 qualifying assays · 12 documents · best pChEMBL 9.4
Experimental evidence source: ChEMBL
Insulin receptor
Homo sapiens · SINGLE PROTEIN · 7 qualifying assays · 6 documents · best pChEMBL 8.15
Experimental evidence source: ChEMBL
Insulin-like growth factor 1 receptor
Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 8.1
Experimental evidence source: ChEMBL
Epidermal growth factor receptor
Homo sapiens · SINGLE PROTEIN · 22 qualifying assays · 14 documents · best pChEMBL 7.72
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Ceritinib is identified by CAS 1032900-25-6, with molecular formula C28H36ClN5O3S, molecular weight 558.1, InChIKey VERWOWGGCGHDQE-UHFFFAOYSA-N.
ChEMBL contains qualifying experimental assay evidence associated with ALK tyrosine kinase receptor, Proto-oncogene tyrosine-protein kinase ROS, Insulin receptor, Insulin-like growth factor 1 receptor, Epidermal growth factor receptor. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
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