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Home/Compounds/CAS 10444-89-0
Formula C3H2F3N3SMW 169.13Research-use catalog entryCOA/SDS by request

1,3,4-Thiadiazol-2-amine, 5-(trifluoromethyl)-

CAS Number: 10444-89-0

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Loading RDKit molecule structure...
InChIKey: LTEUXHSAYOSFGQ-UHFFFAOYSA-NC3H2F3N3S | MW 169.13

Chemical Absolute Identifiers

CAS Number

10444-89-0

PubChem CID

82634

Molecular Formula

C3H2F3N3S

Molecular Weight

169.13 g/mol

Exact Mass

168.992153

InChIKey

LTEUXHSAYOSFGQ-UHFFFAOYSA-N

IUPAC Name

5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine

SMILES String

C1(=NN=C(S1)N)C(F)(F)F

Physical Properties

Water Solubility

17 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

1,3,4-Thiadiazol-2-amine, 5-(trifluoromethyl)- (CAS 10444-89-0) is listed in the Advanced Chemicals portfolio, with molecular formula C3H2F3N3S and molecular weight 169. 13 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Escherichia coli K-12) — 3 assays; Replicase polyprotein 1ab (Severe acute respiratory syndrome coronavirus 2) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Escherichia coli K-12 · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Replicase polyprotein 1ab

Severe acute respiratory syndrome coronavirus 2 · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

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PPE

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First Aid

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Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, hydrogen fluoride, nitrogen oxides, sulfur oxides.

Disposal

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Fire Fighting

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Accidental Release

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For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

1,3,4-Thiadiazol-2-amine, 5-(trifluoromethyl)-

Names & Synonyms

2-Amino-5-trifluoromethyl-1,3,4-thiadiazole2-Amino-5-(trifluoromethyl)-1,3,4-thiadiazole1,3,4-Thiadiazole, 2-amino-5-(trifluoromethyl)-5-Trifluoromethyl-[1,3,4]thiadiazol-2-ylamine5-(trifluoromethyl)-1,3,4-thiadiazole-2-ylamine
Show all synonyms
Maybridge1_0034482-AMINO-5-TRIFLUOROMETHYL-1,3,4-THIADIAZ OLESDCCGMLS-0065806.P0012-Amino-5-trifluoromethyl-1,3,4-triazole5-trifluoromethyl2-amino-1,3,4-thiadiazoleA24622-Amino-5-(trifluoromethyl)-1,4-thiadiazole2-amino-5-trifluoromethyl[1,3,4]thiadiazole2-trifluoromethyl-5-amino-1,3,4-thiadiazole5-trifluoromethyl-2-amino-1,3,4-thiadiazole1,4-Thiadiazol-2-amine, 5-(trifluoromethyl)-2-amino-5-(trifluormethyl)-1,3,4-thiadiazole5-trifluoromethyl- 2-amino-1,3,4-thiadiazole5-trifluoromethyl-1,3,4-thiadiazole-2-ylamine
External Identifiers
EC NUMBER: 233-930-2DSSTOX SUBSTANCE ID: DTXSID4065078CHEMBL ID: CHEMBL1311331WIKIDATA ID: Q72442885
Experimental Spectrum References
13C NMR Spectra1H NMR SpectraATR-IR Spectra — Bio-Rad Laboratories, Inc.FTIR Spectra — Bio-Rad Laboratories, Inc.Raman Spectra — Bio-Rad Laboratories, Inc.UV-VIS Spectra
Literature & Patent References
DOI 10.1021/acsmedchemlett.2c00429Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe?PMID 36518695Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe?PMID 37943932PMID 37943932

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

ButhidazolamineCAS 39222-73-6
2-Bromo-5-(trifluoromethyl)-1,3,4-thiadiazoleCAS 37461-61-3
1,3,4-Thiadiazole-2,5-diamineCAS 2937-81-7
2-Amino-5-bromo-1,3,4-thiadiazoleCAS 37566-39-5
5-(Difluoromethyl)-1,3,4-thiadiazol-2-amineCAS 25306-15-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 39222-73-6ButhidazolamineCAS 37461-61-32-Bromo-5-(trifluoromethyl)-1,3,4-thiadiazoleCAS 2937-81-71,3,4-Thiadiazole-2,5-diamineCAS 37566-39-52-Amino-5-bromo-1,3,4-thiadiazoleCAS 25306-15-45-(Difluoromethyl)-1,3,4-thiadiazol-2-amineCAS 108-33-81,3,4-Thiadiazole, 2-amino-5-methyl-CAS 170235-26-4Methyl 2-bromothiazole-4-carboxylateCAS 22900-83-0Ethyl 2-bromo-4-methyl-1,3-thiazole-5-carboxylateCAS 29676-71-9(2-Amino-1,3-thiazol-4-yl)acetic acidCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamate

RFQ questions for CAS 10444-89-0

What are the key identifiers for 1,3,4-Thiadiazol-2-amine, 5-(trifluoromethyl)- (CAS 10444-89-0)?

1,3,4-Thiadiazol-2-amine, 5-(trifluoromethyl)- is identified by CAS 10444-89-0, with molecular formula C3H2F3N3S, molecular weight 169.13, InChIKey LTEUXHSAYOSFGQ-UHFFFAOYSA-N.

Does CAS 10444-89-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Replicase polyprotein 1ab. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 10444-89-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 1,3,4-Thiadiazol-2-amine, 5-(trifluoromethyl)-?

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Is CAS 10444-89-0 available for quotation?

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