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Home/Compounds/CAS 106243-16-7
Formula C15H24N4SMW 292.4Research-use catalog entryCOA/SDS by request

Thioperamide

CAS Number: 106243-16-7

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Loading RDKit molecule structure...
InChIKey: QKDDJDBFONZGBW-UHFFFAOYSA-NC15H24N4S | MW 292.4

Chemical Absolute Identifiers

CAS Number

106243-16-7

PubChem CID

3035905

Molecular Formula

C15H24N4S

Molecular Weight

292.4 g/mol

Exact Mass

292.172168

InChIKey

QKDDJDBFONZGBW-UHFFFAOYSA-N

IUPAC Name

N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide

SMILES String

C1CCC(CC1)NC(=S)N2CCC(CC2)C3=CN=CN3

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Thioperamide (CAS 106243-16-7) is listed in the Advanced Chemicals portfolio, with molecular formula C15H24N4S and molecular weight 292. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Organic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Histamine H3 receptor (Cavia porcellus) — 8 assays; Histamine H3 receptor (Rattus norvegicus) — 29 assays; Histamine H3 receptor (Homo sapiens) — 57 assays; Histamine H4 receptor (Homo sapiens) — 45 assays; Histamine H3 receptor (Mus musculus) — 12 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Histamine H3 receptor

Cavia porcellus · SINGLE PROTEIN · 8 qualifying assays · 8 documents · best pChEMBL 9.06

Experimental evidence source: ChEMBL

Histamine H3 receptor

Rattus norvegicus · SINGLE PROTEIN · 29 qualifying assays · 25 documents · best pChEMBL 8.81

Experimental evidence source: ChEMBL

Histamine H3 receptor

Homo sapiens · SINGLE PROTEIN · 57 qualifying assays · 37 documents · best pChEMBL 8.71

Experimental evidence source: ChEMBL

Histamine H4 receptor

Homo sapiens · SINGLE PROTEIN · 45 qualifying assays · 24 documents · best pChEMBL 8.4

Experimental evidence source: ChEMBL

Histamine H3 receptor

Mus musculus · SINGLE PROTEIN · 12 qualifying assays · 10 documents · best pChEMBL 8.32

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Thioperamide

Names & Synonyms

MR 128421-Piperidinecarbothioamide, N-cyclohexyl-4-(1H-imidazol-4-yl)-N-Cyclohexy-4-(imidazol-4-yl)-1-piperidinecarbothioamideN-cyclohexyl-4-(3H-imidazol-4-yl)piperidine-1-carbothioamideN-Cyclohexyl-4-(1H-imidazol-5-yl)-1-piperidinecarbothioamide
Show all synonyms
Lopac-T-123N-cyclohexyl-4-(1H-imidazol-4-yl)piperidine-1-carbothioamideLopac0_001214SDCCGSBI-0051181.P0021-PIPERIDINECARBOTHIOAMIDE, N-CYCLOHEXYL-4-(1H-IMIDAZOL-5-YL)-FJZ
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID50147555CHEMBL ID: CHEMBL260374CHEBI ID: CHEBI:81391UNII: II4319BWUIHMDB ID: HMDB0259023KEGG ID: C17933NCI THESAURUS CODE: C218860WIKIDATA ID: Q7784686Tocris-0644
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1021/acs.jmedchem.3c00430Dual Piperidine-Based Histamine H<sub>3</sub> and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.DOI 10.1021/acsmedchemlett.3c00413Discovery of a Tritiated Radioligand with High Affinity and Selectivity for the Histamine H&lt;sub&gt;3&lt;/sub&gt; Receptor.PMID 37418295Dual Piperidine-Based Histamine H<sub>3</sub> and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.PMID 37974943Discovery of a Tritiated Radioligand with High Affinity and Selectivity for the Histamine H&lt;sub&gt;3&lt;/sub&gt; Receptor.DOI 10.1021/acs.jmedchem.1c01898Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors.PMID 35166541Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

DicyclohexylthioureaCAS 1212-29-9
1-Cyclohexyl-3-phenyl-2-thioureaCAS 722-03-2
4-CyclohexylthiosemicarbazideCAS 21198-18-5
Thiourea, N-cyclohexyl-N'-(2-(4-morpholinyl)ethyl)-CAS 21545-54-0
CyclopropylthioureaCAS 56541-14-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 21829-25-4NifedipineCAS 23593-75-1ClotrimazoleCAS 79794-75-5LoratadineCAS 132539-06-1OlanzapineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 106243-16-7

What are the key identifiers for Thioperamide (CAS 106243-16-7)?

Thioperamide is identified by CAS 106243-16-7, with molecular formula C15H24N4S, molecular weight 292.4, InChIKey QKDDJDBFONZGBW-UHFFFAOYSA-N.

Does CAS 106243-16-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Histamine H3 receptor, Histamine H3 receptor, Histamine H3 receptor, Histamine H4 receptor, Histamine H3 receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 106243-16-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Thioperamide?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 106243-16-7 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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