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Home/Compounds/CAS 106308-44-5
Formula C10H8F2N4OMW 238.19Research-use catalog entryCOA/SDS by request

Rufinamide

CAS Number: 106308-44-5

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Loading RDKit molecule structure...
InChIKey: POGQSBRIGCQNEG-UHFFFAOYSA-NC10H8F2N4O | MW 238.19

Chemical Absolute Identifiers

CAS Number

106308-44-5

PubChem CID

129228

Molecular Formula

C10H8F2N4O

Molecular Weight

238.19 g/mol

Exact Mass

238.066617

InChIKey

POGQSBRIGCQNEG-UHFFFAOYSA-N

IUPAC Name

1-[(2,6-difluorophenyl)methyl]triazole-4-carboxamide

SMILES String

C1=CC(=C(C(=C1)F)CN2C=C(N=N2)C(=O)N)F

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Rufinamide (CAS 106308-44-5) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C10H8F2N4O and molecular weight 238. 19 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Sodium channel protein type 1 subunit alpha (Homo sapiens) — 4 assays; Nuclear receptor subfamily 1 group I member 2 (Homo sapiens) — 3 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2B (Homo sapiens) — 2 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Sodium channel protein type 1 subunit alpha

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Nuclear receptor subfamily 1 group I member 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2B

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Rufinamide

Names & Synonyms

InovelonBanzel1-(2,6-Difluorobenzyl)-1H-1,2,3-triazole-4-carboxamideCgp 33101RUF 331
Show all synonyms
RufinamidaE2080E 20801H-1,2,3-Triazole-4-carboxamide, 1-((2,6-difluorophenyl)methyl)-1H-1,2,3-Triazole-4-carboxamide, 1-[(2,6-difluorophenyl)methyl]-1-((2,6-difluorophenyl)methyl)triazole-4-carboxamiderufinamidumSYN111-[(2,6-difluorophenyl)methyl]-1H-1,2,3-Triazole-4-carboxamideXileps12561-[(2,6-difluorophenyl)methyl]-1H-1,2,3-triazole-4 carboxamideRufinamide [USAN:INN:BAN]Rufinamide?
External Identifiers
EC NUMBER: 808-195-1DSSTOX SUBSTANCE ID: DTXSID1046506CHEMBL ID: CHEMBL1201754CHEBI ID: CHEBI:134966UNII: WFW942PR79DRUGBANK ID: DB06201HMDB ID: HMDB0257362KEGG ID: D05775METABOLOMICS WORKBENCH ID: 149673NCI THESAURUS CODE: C75167PHARMGKB ID: PA166131606RXCUI: 69036WIKIDATA ID: Q408565
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.1016/j.bmcl.2022.128946Discovery of triazenyl triazoles as Na<sub>v</sub>1.1 channel blockers for treatment of epilepsy.PMID 35985458Discovery of triazenyl triazoles as Na<sub>v</sub>1.1 channel blockers for treatment of epilepsy.DOI 10.1021/acs.jmedchem.0c02245Designing Out PXR Activity on Drug Discovery Projects: A Review of Structure-Based Methods, Empirical and Computational Approaches.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 34003642Designing Out PXR Activity on Drug Discovery Projects: A Review of Structure-Based Methods, Empirical and Computational Approaches.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

CGP-47292 methyl esterCAS 217448-86-7
4-Cyano-1-(2,6-difluorobenzyl)-1H-1,2,3-triazoleCAS 202003-06-3
2-(Bromomethyl)-1,3-difluorobenzeneCAS 85118-00-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 217448-86-7CGP-47292 methyl esterCAS 202003-06-34-Cyano-1-(2,6-difluorobenzyl)-1H-1,2,3-triazoleCAS 102767-28-2LevetiracetamCAS 107724-20-9EplerenoneCAS 139481-59-7CandesartanCAS 23593-75-1ClotrimazoleCAS 100643-71-8DesloratadineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 106308-44-5

What are the key identifiers for Rufinamide (CAS 106308-44-5)?

Rufinamide is identified by CAS 106308-44-5, with molecular formula C10H8F2N4O, molecular weight 238.19, InChIKey POGQSBRIGCQNEG-UHFFFAOYSA-N.

Does CAS 106308-44-5 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Sodium channel protein type 1 subunit alpha, Nuclear receptor subfamily 1 group I member 2, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, Alpha-1A adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 106308-44-5?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Rufinamide?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 106308-44-5 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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