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Home/Compounds/CAS 106516-24-9
Formula C24H26ClFN4OMW 440.9Research-use catalog entryCOA/SDS by request

Sertindole

CAS Number: 106516-24-9

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Loading RDKit molecule structure...
InChIKey: GZKLJWGUPQBVJQ-UHFFFAOYSA-NC24H26ClFN4O | MW 440.9

Chemical Absolute Identifiers

CAS Number

106516-24-9

PubChem CID

60149

Molecular Formula

C24H26ClFN4O

Molecular Weight

440.9 g/mol

Exact Mass

440.177917

InChIKey

GZKLJWGUPQBVJQ-UHFFFAOYSA-N

IUPAC Name

1-[2-[4-[5-chloro-1-(4-fluorophenyl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one

SMILES String

C1CN(CCC1C2=CN(C3=C2C=C(C=C3)Cl)C4=CC=C(C=C4)F)CCN5CCNC5=O

Physical Properties

Water Solubility

9.63 × 10⁻³ g/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Sertindole (CAS 106516-24-9) is listed in the Advanced Chemicals portfolio, with molecular formula C24H26ClFN4O and molecular weight 440. 90 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: 5-hydroxytryptamine receptor 2C (Homo sapiens) — 4 assays; 5-hydroxytryptamine receptor 2A (Rattus norvegicus) — 2 assays; Alpha-1B adrenergic receptor (Mesocricetus auratus) — 3 assays; Alpha-1A adrenergic receptor (Bos taurus) — 3 assays; D(2) dopamine receptor (Homo sapiens) — 5 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

5-hydroxytryptamine receptor 2C

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 9.7

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 9.7

Experimental evidence source: ChEMBL

Alpha-1B adrenergic receptor

Mesocricetus auratus · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 9.48

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Bos taurus · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 9.43

Experimental evidence source: ChEMBL

D(2) dopamine receptor

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 5 documents · best pChEMBL 9.42

Experimental evidence source: ChEMBL

Safety & Handling

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and stability.
  • Carbon monoxide, carbon dioxide, hydrogen chloride, hydrogen fluoride, nitrogen oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional institution with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus during firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Sertindole

Names & Synonyms

SerLectSerdolectSertindolSertindolumLu 23-174
Show all synonyms
zerdol1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one1-(2-(4-(5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl)piperidin-1-yl)ethyl)imidazolidin-2-one1-(2-(4-(5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl)-1-piperidinyl)ethyl)-2-imidazolidinone1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one1-[2-[4-[5-chloro-1-(4-fluorophenyl)-1h-indol-3-yl]-1-piperidinyl]ethyl]-2-imidazolidinone1-(2-(4-(5-chloro-1-(4-fluorophenyl)-indol-3-yl)-1-piperidyl)ethyl)imidazolidin-2-one1-(2-(4-(5-chloro-1-(4-fluorophenyl)indol-3-yl)piperidin-1-yl)ethyl)imidazolidin-2-one1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl}ethyl)-2-imidazolidinoneSertindol [INN-Spanish]Sertindolum [INN-Latin]1-(2-(4-(5-Chloro-1-(p-fluorophenyl)indol-3-yl)piperidino)ethyl)-2-imidazolidinone2-Imidazolidinone, 1-(2-(4-(5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl)-1-piperidinyl)ethyl)-
External Identifiers
EC NUMBER: 634-595-9DSSTOX SUBSTANCE ID: DTXSID6048967CHEMBL ID: CHEMBL12713CHEBI ID: CHEBI:9122UNII: GVV4Z879SPDRUGBANK ID: DB06144HMDB ID: HMDB0015618KEGG ID: C07567KEGG ID: D00561METABOLOMICS WORKBENCH ID: 43657NCI THESAURUS CODE: C73295PHARMGKB ID: PA164784002WIKIDATA ID: Q418050Lu-23-174
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1039/d3md00677hIndole-containing pharmaceuticals: targets, pharmacological activities, and SAR studies.PMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38516587Indole-containing pharmaceuticals: targets, pharmacological activities, and SAR studies.DOI 10.1021/acs.jmedchem.3c00281Discovery of New <i>Fusobacterium nucleatum</i> Inhibitors to Attenuate Migratory Capability of Colon Cancer Cells by the Drug Repositioning Strategy.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.6019/EOS300108ECBD screening data for assay EOS300108PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
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  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

1-(3-Chlorophenyl)imidazolidin-2-oneCAS 14088-98-3
1-(2-Chloroethyl)imidazolidin-2-oneCAS 2387-20-4
1-Benzylimidazolidin-2-oneCAS 2385-38-8
1-Ethylimidazolidin-2-oneCAS 872-69-5
1-(4-Bromophenyl)imidazolidin-2-oneCAS 530081-14-2

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 132539-06-1OlanzapineCAS 111974-69-7QuetiapineCAS 117-89-5TrifluoperazineCAS 79794-75-5LoratadineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 106516-24-9

What are the key identifiers for Sertindole (CAS 106516-24-9)?

Sertindole is identified by CAS 106516-24-9, with molecular formula C24H26ClFN4O, molecular weight 440.9, InChIKey GZKLJWGUPQBVJQ-UHFFFAOYSA-N.

Does CAS 106516-24-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 2A, Alpha-1B adrenergic receptor, Alpha-1A adrenergic receptor, D(2) dopamine receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 106516-24-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Sertindole?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 106516-24-9 available for quotation?

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