Research chemical
CAS Number: 1088216-72-1
Product details
For laboratory research and professional procurement workflows.
PubChem CID
25348574
Exact Mass
276.126263
InChIKey
HPQZTEVMVAVGJO-UHFFFAOYSA-N
IUPAC Name
N-(4-methyl-2-pyridinyl)-2-naphthalen-2-ylacetamide
SMILES String
Cc1ccnc(NC(=O)Cc2ccc3ccccc3c2)c1
Appearance
Catalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Riok2-IN-1 is identified by CAS 1088216-72-1, with molecular formula C18H16N2O, molecular weight 276.3, InChIKey HPQZTEVMVAVGJO-UHFFFAOYSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Serine/threonine-protein kinase RIO2, Mitogen-activated protein kinase 8, Mitogen-activated protein kinase 10, Glycogen synthase kinase-3 alpha, SNF-related serine/threonine-protein kinase. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
Solid
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Heavy atom count
21
H-bond acceptors
3
H-bond donors
1
Rotatable bonds
3
Ring count
3
Aromatic rings
3
Topological polar surface area
41.99 Ų
Computed LogP
3.72
Fragment-like structure rule
Yes
Lead-like structure rule
Yes
Drug-like structure rule
Yes
Structure family
n heterocycle ligand
Precious metal motif
No
Transition metal motif
No
Phosphine ligand motif
No
N-heterocycle motif
Yes
Boronic acid motif
No
Computed structure descriptors generated from molecular structure. These are not experimental physical property values, supplier specifications, SDS data, or bioactivity claims.
Structural features
Riok2-IN-1 (CAS 1088216-72-1) is maintained as a cataloged research chemical with formula C18H16N2O, molecular weight 276. 30 g/mol, PubChem CID 25348574.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Use this page for identity verification, supplier-aware sourcing review, and RFQ preparation; structure-derived tags include nitrogen-containing heterocycle, fragment-like structure profile, lead-like structure profile, drug-like rule profile.
Documentation needs
SDS signal word: Warning; hazard codes: H302, H315, H319; for research use only.
ChEMBL reports experimental activity evidence for: Serine/threonine-protein kinase RIO2 (Homo sapiens) — 6 assays; Mitogen-activated protein kinase 8 (Homo sapiens) — 2 assays; Mitogen-activated protein kinase 10 (Homo sapiens) — 2 assays; Glycogen synthase kinase-3 alpha (Homo sapiens) — 2 assays; SNF-related serine/threonine-protein kinase (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Serine/threonine-protein kinase RIO2
Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 4 documents · best pChEMBL 6.85
Experimental evidence source: ChEMBL
Mitogen-activated protein kinase 8
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.66
Experimental evidence source: ChEMBL
Mitogen-activated protein kinase 10
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.47
Experimental evidence source: ChEMBL
Glycogen synthase kinase-3 alpha
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.06
Experimental evidence source: ChEMBL
SNF-related serine/threonine-protein kinase
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.05
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.
Preliminary Safety Reference
For supplier-issued SDS or COA, submit a documentation request.
Safety Reference / SDS RequestSubmit the CAS number, quantity, purity requirement, and destination country for sourcing review.