Research chemical
CAS Number: 109010-10-8
Product details
For laboratory research and professional procurement workflows.
PubChem CID
5362124
Exact Mass
424.199822
InChIKey
XPCFTKFZXHTYIP-PMACEKPBSA-N
IUPAC Name
2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid
SMILES String
CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CCc2ccccc2N(CC(=O)O)C1=O
No physical property values available.
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Catalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Benazepril is identified by CAS 109010-10-8, with molecular formula C24H28N2O5, molecular weight 424.5, InChIKey XPCFTKFZXHTYIP-PMACEKPBSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Angiotensin-converting enzyme, Angiotensin-converting enzyme, Angiotensin-converting enzyme, Type-2 angiotensin II receptor, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
Heavy atom count
31
H-bond acceptors
7
H-bond donors
2
Rotatable bonds
9
Ring count
3
Aromatic rings
2
Topological polar surface area
95.94 Ų
Computed LogP
2.57
Fragment-like structure rule
No
Lead-like structure rule
No
Drug-like structure rule
Yes
Structure family
n heterocycle ligand
Precious metal motif
No
Transition metal motif
No
Phosphine ligand motif
No
N-heterocycle motif
Yes
Boronic acid motif
No
Computed structure descriptors generated from molecular structure. These are not experimental physical property values, supplier specifications, SDS data, or bioactivity claims.
Structural features
Benazepril (CAS 109010-10-8) is maintained as a commercial cas reference with formula C24H28N2O5, molecular weight 424. 50 g/mol, PubChem CID 5362124.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Use this page for CAS identity lookup, internal catalog search, and commercial discovery workflows; structure-derived tags include nitrogen-containing heterocycle, drug-like rule profile.
Documentation needs
Review supplier documentation before handling; for research use only.
ChEMBL reports experimental activity evidence for: Angiotensin-converting enzyme (Rattus norvegicus) — 5 assays; Angiotensin-converting enzyme (Homo sapiens) — 2 assays; Angiotensin-converting enzyme (Oryctolagus cuniculus) — 3 assays; Type-2 angiotensin II receptor (Homo sapiens) — 2 assays; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Angiotensin-converting enzyme
Rattus norvegicus · SINGLE PROTEIN · 5 qualifying assays · 2 documents · best pChEMBL 8.77
Experimental evidence source: ChEMBL
Angiotensin-converting enzyme
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 8.77
Experimental evidence source: ChEMBL
Angiotensin-converting enzyme
Oryctolagus cuniculus · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 8.7
Experimental evidence source: ChEMBL
Type-2 angiotensin II receptor
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.4
Experimental evidence source: ChEMBL
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.16
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.
Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.