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Home/Compounds/CAS 1093070-14-4
Formula C22H22N2O2MW 346.4Research-use catalog entryCOA/SDS by request

5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide

CAS Number: 1093070-14-4

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Loading RDKit molecule structure...
InChIKey: KGPYBLOBHQLIET-OAHLLOKOSA-NC22H22N2O2 | MW 346.4

Chemical Absolute Identifiers

CAS Number

1093070-14-4

PubChem CID

44235889

Molecular Formula

C22H22N2O2

Molecular Weight

346.4 g/mol

Exact Mass

346.168128

InChIKey

KGPYBLOBHQLIET-OAHLLOKOSA-N

IUPAC Name

5-acetamido-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide

SMILES String

CC(=O)Nc1ccc(C)c(C(=O)N[C@H](C)c2cccc3ccccc23)c1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide (CAS 1093070-14-4) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C22H22N2O2 and molecular weight 346. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Replicase polyprotein 1ab (Severe acute respiratory syndrome coronavirus 2) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Replicase polyprotein 1ab

Severe acute respiratory syndrome coronavirus 2 · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 5.76

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide

Names & Synonyms

(R)-5-acetamido-2-methyl-N-(1-(naphthalen-1-yl)ethyl)benzamide5-ACETAMIDO-2-METHYL-N-[(1R)-1-(NAPHTHALEN-1-YL)ETHYL]BENZAMIDE5-N-Acetylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide5-acetamido-2-methyl-N-((1R)-1-(naphthalen-1-yl)ethyl)benzamide5-N-acetylamino-2-methyl-N-((R)-1-(1-naphthyl)ethyl)benzamide
Show all synonyms
5-(Acetylamino)-2-methyl-N-((1R)-1-(1-naphthalenyl)ethyl)benzamidePLpro inhibitorPLpro inhibitor 6Naphthalene and Benzamide Derivative, 24S05155-acetamido-2-methyl-N-[(1R)-1-(1-naphthyl)ethyl]benzamide
External Identifiers
CHEMBL ID: CHEMBL551592CHEBI ID: CHEBI:167314WIKIDATA ID: Q106029796GRL-0617-Ac
Literature & Patent References
DOI 10.1016/j.bmc.2024.117909Design of inhibitors of SARS-CoV-2 papain-like protease deriving from GRL0617: Structure-activity relationships.PMID 39288705Design of inhibitors of SARS-CoV-2 papain-like protease deriving from GRL0617: Structure-activity relationships.DOI 10.1016/j.ejmech.2023.115629An overview of anti-SARS-CoV-2 and anti-inflammatory potential of baicalein and its metabolite baicalin: Insights into molecular mechanisms.PMID 37437351An overview of anti-SARS-CoV-2 and anti-inflammatory potential of baicalein and its metabolite baicalin: Insights into molecular mechanisms.DOI 10.1021/acs.jmedchem.2c00303Progress and Challenges in Targeting the SARS-CoV-2 Papain-like Protease.PMID 35620927Progress and Challenges in Targeting the SARS-CoV-2 Papain-like Protease.DOI 10.1021/jm900611tStructure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease.PMID 19645480Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

FtaxilideCAS 19368-18-4
PhthalylsulfacetamideCAS 131-69-1
OsalmidCAS 526-18-1
AmicarthiazolCAS 21452-14-2
SalicylanilideCAS 87-17-2

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 1093070-14-4

What are the key identifiers for 5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide (CAS 1093070-14-4)?

5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide is identified by CAS 1093070-14-4, with molecular formula C22H22N2O2, molecular weight 346.4, InChIKey KGPYBLOBHQLIET-OAHLLOKOSA-N.

Does CAS 1093070-14-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Replicase polyprotein 1ab. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1093070-14-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

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