Research chemical

Tautomycin

CAS Number: 109946-35-2

Product details

Identity & specification

Molecular formula: C41H66O13
Molecular weight: 767 g/mol
Product type: Research-use catalog compound
Documentation: COA / SDS available by request

For laboratory research and professional procurement workflows.

Technical identifiers

Show PubChem, InChIKey, IUPAC, and SMILES

PubChem CID

440646

Exact Mass

766.450342

InChIKey

RFCWHQNNCOJYTR-IRCAEPKSSA-N

IUPAC Name

[(3R,4R,5R,8S,9S,12R)-12-[(2S,3S,6R,8S,9R)-3,9-dimethyl-8-[(3S)-3-methyl-4-oxopentyl]-1,7-dioxaspiro[5.5]undecan-2-yl]-5,9-dihydroxy-4-methoxy-2,8-dimethyl-7-oxotridecan-3-yl] (3R)-3-hydroxy-3-(4-methyl-2,5-dioxofuran-3-yl)propanoate

SMILES String

C[C@@H]1CC[C@@]2(CC[C@@H]([C@@H](O2)[C@H](C)CC[C@@H]([C@H](C)C(=O)C[C@H]([C@H]([C@@H](C(C)C)OC(=O)C[C@H](C3=C(C(=O)OC3=O)C)O)OC)O)O)C)O[C@H]1CC[C@H](C)C(=O)C

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Computed Structure Descriptors

Show calculated structure fields

Heavy atom count

H-bond acceptors

H-bond donors

Rotatable bonds

Ring count

Aromatic rings

Topological polar surface area

192.19 Å²

Computed LogP

4.79

Fragment-like structure rule

Lead-like structure rule

Drug-like structure rule

Structure family

other structure rule

Precious metal motif

Transition metal motif

Phosphine ligand motif

N-heterocycle motif

Boronic acid motif

Computed structure descriptors generated from molecular structure. These are not experimental physical property values, supplier specifications, SDS data, or bioactivity claims.

Catalog Facts

Structural features

Tautomycin (CAS 109946-35-2) is maintained as a cataloged research chemical with formula C41H66O13, molecular weight 767. 00 g/mol, PubChem CID 440646.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Use this page for identity verification, supplier-aware sourcing review, and RFQ preparation.

Documentation needs

Review supplier documentation before handling; for research use only.

Applications & Classification

Supplier Catalog Sourcing Commercial Research ChemicalsResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow

Biological target reference

ChEMBL reports experimental activity evidence for: Serine-threonine protein phosphatase 2A regulatory subunit (Gallus gallus) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Serine-threonine protein phosphatase 2A regulatory subunit

Gallus gallus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 9.15

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Synonyms & references

Names & Synonyms

Tautomycin from Streptomyces spiroverticillatus

External Identifiers

EC NUMBER: 620-961-5CHEMBL ID: CHEMBL505512CHEBI ID: CHEBI:9414KEGG ID: C05372METABOLOMICS WORKBENCH ID: 68702WIKIDATA ID: Q7688965

Literature & Patent References

DOI 10.1021/acs.jmedchem.1c00631Strategies for Targeting Serine/Threonine Protein Phosphatases with Small Molecules in Cancer.PMID 34156850Strategies for Targeting Serine/Threonine Protein Phosphatases with Small Molecules in Cancer.DOI 10.1021/np8007478Characterization of the tautomycetin biosynthetic gene cluster from Streptomyces griseochromogenes provides new insight into dialkylmaleic anhydride biosynthesis.PMID 19191560Characterization of the tautomycetin biosynthetic gene cluster from Streptomyces griseochromogenes provides new insight into dialkylmaleic anhydride biosynthesis.DOI 10.1016/s0960-894x(03)00105-7The selective inhibition of phosphatases by natural toxins: the anhydride domain of tautomycin is not a primary factor in controlling PP1/PP2A selectivity.DOI 10.1016/s0960-894x(03)00106-9A new model of the tautomycin-PP1 complex that is not analogous to the corresponding okadaic acid structure.PMID 12699763The selective inhibition of phosphatases by natural toxins: the anhydride domain of tautomycin is not a primary factor in controlling PP1/PP2A selectivity.PMID 12699764A new model of the tautomycin-PP1 complex that is not analogous to the corresponding okadaic acid structure.

Documentation & Compliance Facts

Compliance Facts

Signal word: Danger

Supplier SDS reference cue; confirm supplier documentation before use.

Hazard statements: H300

Supplier SDS hazard code reference; confirm full text in supplier documentation.

Precautionary statements: P264, P270, P301+P316, P321, P330, P405, P501

Supplier SDS precautionary code reference; confirm full text in supplier documentation.

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

1We review the CAS identity, quantity, and documentation request.
2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
3We review destination and shipment documentation needs when applicable.
4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Linked by recorded structural or research relationships, not interchangeable products. Check the exact CAS, specification and availability on the linked product page.

Procurement questions

What are the key identifiers for Tautomycin (CAS 109946-35-2)?

Tautomycin is identified by CAS 109946-35-2, with molecular formula C41H66O13, molecular weight 767, InChIKey RFCWHQNNCOJYTR-IRCAEPKSSA-N.

Does CAS 109946-35-2 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Serine-threonine protein phosphatase 2A regulatory subunit. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 109946-35-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Tautomycin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 109946-35-2 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

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