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Home/Compounds/CAS 111974-69-7
Formula C21H25N3O2SMW 383.5Research-use catalog entryCOA/SDS by request

Quetiapine

CAS Number: 111974-69-7

Sourcing & RFQ

Submit an RFQ to review pricing, availability, lead time, pack size, purity, COA, and supplier SDS for this catalog entry.

Available options

Available Options

Package
50 mg
Purity
95%
Price
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Availability
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Loading RDKit molecule structure...
InChIKey: URKOMYMAXPYINW-UHFFFAOYSA-NC21H25N3O2S | MW 383.5

Chemical Absolute Identifiers

CAS Number

111974-69-7

PubChem CID

5002

Molecular Formula

C21H25N3O2S

Molecular Weight

383.5 g/mol

Exact Mass

383.166748

InChIKey

URKOMYMAXPYINW-UHFFFAOYSA-N

IUPAC Name

2-[2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethoxy]ethanol

SMILES String

C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42

Physical Properties

Water Solubility

49.4 mol/L

pKa

7.06

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Quetiapine (CAS 111974-69-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C21H25N3O2S and molecular weight 383. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Histamine H1 receptor (Homo sapiens) — 9 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 8 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 15 assays; Alpha-1A adrenergic receptor (Rattus norvegicus) — 2 assays; Alpha-2B adrenergic receptor (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Histamine H1 receptor

Homo sapiens · SINGLE PROTEIN · 9 qualifying assays · 9 documents · best pChEMBL 8.34

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 8 qualifying assays · 3 documents · best pChEMBL 7.7

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 15 qualifying assays · 12 documents · best pChEMBL 7.51

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 7.46

Experimental evidence source: ChEMBL

Alpha-2B adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 7.34

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides.

Disposal

  • Waste product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
Show additional safety reference fields

Fire Fighting

  • If necessary, wear a self-contained breathing apparatus during firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Quetiapine

Names & Synonyms

quetiapinaNorsicquetiapinum2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolQuetiapine extended release
Show all synonyms
2-(2-(4-Dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazinyl)ethoxy)ethanolEthanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-Ethanol, 2-(2-(4-dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazinyl)ethoxy)-Seroquel XL2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol2-(2-(4-DIBENZO(B,F)(1,4)THIAZEPIN-11-YLPIPERAZIN-1-YL)ETHOXY)ETHANOLTenprolide xlBiquelle xlBrancico xlMintreleq xlSeotiapim xlAtrolak xlEbesque xlPsyquet xl
External Identifiers
EC NUMBER: 601-143-7DSSTOX SUBSTANCE ID: DTXSID9023546CHEMBL ID: CHEMBL716CHEBI ID: CHEBI:8707UNII: BGL0JSY5SIDRUGBANK ID: DB01224HMDB ID: HMDB0005021KEGG ID: C07397KEGG ID: D08456METABOLOMICS WORKBENCH ID: 38707NCI THESAURUS CODE: C61917PHARMGKB ID: PA451201RXCUI: 51272WIKIDATA ID: Q408535
Experimental Spectrum References
1D NMR SpectraATR-IR Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.5281/zenodo.13943903Linking interpersonal differences in gut microbiota composition and drug biotransformation activityPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1021/acs.jmedchem.3c011782B Determined: The Future of the Serotonin Receptor 2B in Drug Discovery.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 375844062B Determined: The Future of the Serotonin Receptor 2B in Drug Discovery.DOI 10.1016/j.ejmech.2022.114218Design, synthesis, and behavioral evaluation of dual-acting compounds as phosphodiesterase type 10A (PDE10A) inhibitors and serotonin ligands targeting neuropsychiatric symptoms in dementia.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

Quetiapine FumarateCAS 111974-72-2
2-(Chloroethoxy)ethanolCAS 628-89-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 111974-72-2Quetiapine FumarateCAS 100643-71-8DesloratadineCAS 132539-06-1OlanzapineCAS 21829-25-4NifedipineCAS 106516-24-9SertindoleCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 111974-69-7

What are the key identifiers for Quetiapine (CAS 111974-69-7)?

Quetiapine is identified by CAS 111974-69-7, with molecular formula C21H25N3O2S, molecular weight 383.5, InChIKey URKOMYMAXPYINW-UHFFFAOYSA-N.

Does CAS 111974-69-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Histamine H1 receptor, Alpha-1A adrenergic receptor, 5-hydroxytryptamine receptor 2A, Alpha-1A adrenergic receptor, Alpha-2B adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 111974-69-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Quetiapine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 111974-69-7 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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