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Home/Compounds/CAS 1130067-34-3
Formula C26H28N4O2MW 428.5Research-use catalog entryCOA/SDS by request

N-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro(4.5)decan-8-yl)ethyl)naphthalene-2-carboxamide

CAS Number: 1130067-34-3

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Loading RDKit molecule structure...
InChIKey: FAIFAFUXFFWVNQ-UHFFFAOYSA-NC26H28N4O2 | MW 428.5

Chemical Absolute Identifiers

CAS Number

1130067-34-3

PubChem CID

25105715

Molecular Formula

C26H28N4O2

Molecular Weight

428.5 g/mol

Exact Mass

428.221226

InChIKey

FAIFAFUXFFWVNQ-UHFFFAOYSA-N

IUPAC Name

N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]naphthalene-2-carboxamide

SMILES String

O=C(NCCN1CCC2(CC1)C(=O)NCN2c1ccccc1)c1ccc2ccccc2c1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

N-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro(4. 5)decan-8-yl)ethyl)naphthalene-2-carboxamide (CAS 1130067-34-3) is listed in the Advanced Chemicals portfolio, with molecular formula C26H28N4O2 and molecular weight 428. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Phospholipase D2 (Homo sapiens) — 4 assays; Phospholipase D1 (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Phospholipase D2

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 6.96

Experimental evidence source: ChEMBL

Phospholipase D1

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 6

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

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Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

N-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro(4.5)decan-8-yl)ethyl)naphthalene-2-carboxamide

Names & Synonyms

N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)naphthalene-2-carboxamideN-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamideN-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4,5]dec-8-yl)ethyl]-2-naphthalenecarboxamideN-[2-(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-8-yl)ethyl]-2-naphthalenecarboxamideN-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide, 72
Show all synonyms
N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-2-naphthalenecarboxamide
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID50648719CHEMBL ID: CHEMBL511475CHEBI ID: CHEBI:95023WIKIDATA ID: Q27166784
Literature & Patent References
DOI 10.1021/jm100814gDesign, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor.PMID 20735042Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor.DOI 10.1016/j.bmcl.2009.02.125Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity.DOI 10.1038/nchembio.140Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness.PMID 19136975Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness.PMID 19299128Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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  1. 1We review the CAS identity, quantity, and documentation request.
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Text Reference Cues

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Non-public related references

1-Phenyl-1,3,8-triazaspiro(4.5)decan-4-oneCAS 1021-25-6
1,3,8-Triazaspiro(4.5)decane-2,4-dione, 8-(phenylmethyl)-CAS 28936-94-9
7-Benzyl-1,3,7-triazaspiro[4.4]nonane-2,4-dioneCAS 28863-87-8
3-Phenylimidazolidine-2,4-dioneCAS 2221-13-8
1-Phenylimidazolidin-2-oneCAS 1848-69-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1021-25-61-Phenyl-1,3,8-triazaspiro(4.5)decan-4-oneCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 1130067-34-3

What are the key identifiers for N-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro(4.5)decan-8-yl)ethyl)naphthalene-2-carboxamide (CAS 1130067-34-3)?

N-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro(4.5)decan-8-yl)ethyl)naphthalene-2-carboxamide is identified by CAS 1130067-34-3, with molecular formula C26H28N4O2, molecular weight 428.5, InChIKey FAIFAFUXFFWVNQ-UHFFFAOYSA-N.

Does CAS 1130067-34-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Phospholipase D2, Phospholipase D1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1130067-34-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for N-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro(4.5)decan-8-yl)ethyl)naphthalene-2-carboxamide?

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