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Home/Compounds/CAS 1156-19-0
Formula C14H21N3O3SMW 311.4Research-use catalog entryCOA/SDS by request

Tolazamide

CAS Number: 1156-19-0

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Loading RDKit molecule structure...
InChIKey: OUDSBRTVNLOZBN-UHFFFAOYSA-NC14H21N3O3S | MW 311.4

Chemical Absolute Identifiers

CAS Number

1156-19-0

PubChem CID

5503

Molecular Formula

C14H21N3O3S

Molecular Weight

311.4 g/mol

Exact Mass

311.130363

InChIKey

OUDSBRTVNLOZBN-UHFFFAOYSA-N

IUPAC Name

1-(azepan-1-yl)-3-(4-methylphenyl)sulfonylurea

SMILES String

CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CCCCCC2

Physical Properties

Appearance

Tolazamide appears as white to off-white crystalline powder. Odorless or with a slight odor. (NTP, 1992)

Melting Point

17–173 °C

pKa

25

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Tolazamide (CAS 1156-19-0) is listed in the Inhibitors and Agonists portfolio, with molecular formula C14H21N3O3S and molecular weight 311. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for biochemical and pharmacology research workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Bioactivity ScreeningResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Nuclear factor NF-kappa-B p105 subunit (Homo sapiens) — 2 assays; Cytochrome P450 3A4 (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2B (Homo sapiens) — 2 assays; Alpha-2A adrenergic receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Nuclear factor NF-kappa-B p105 subunit

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.75

Experimental evidence source: ChEMBL

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.4

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2B

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Alpha-2A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides.

Disposal

  • The product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
Show additional safety reference fields

Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Tolazamide

Names & Synonyms

TolinaseNorglycinTolanaseTolazolamideDiabewas
Show all synonyms
TolazamidaTolazamidum1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)ureaN-(p-Toluenesulfonyl)-N'-hexamethyleniminourea4-(p-Tolylsulfonyl)-1,1-hexamethylenesemicarbazideU 17835CCRIS 591N-(azepan-1-ylcarbamoyl)-4-methylbenzenesulfonamideBenzenesulfonamide, N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methyl-Urea, 1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)-Benzenesulfonamide, N-(((hexahydro-1H-azepin-1-yl)amino)carbonyl)-4-methyl-1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)ureaN-(((Hexahydro-1H-azepin-1-yl)-amino)carbonyl)-4-methylbenzenesulfonamideBenzenesulfonamide, N-(((hexahydro-1H-azepin-1-yl)-amino)carbonyl)-4-methyl-
External Identifiers
EC NUMBER: 214-588-3DSSTOX SUBSTANCE ID: DTXSID3021358CHEMBL ID: CHEMBL817CHEBI ID: CHEBI:9613UNII: 9LT1BRO48QDRUGBANK ID: DB00839HMDB ID: HMDB0014977KEGG ID: D00379METABOLOMICS WORKBENCH ID: 43125NCI THESAURUS CODE: C29502PHARMGKB ID: PA164774902WIKIDATA ID: Q7814101
Experimental Spectrum References
ATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Forensic Spectral ResearchUV Spectra
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.5281/zenodo.13943903Linking interpersonal differences in gut microbiota composition and drug biotransformation activityPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.1101/2020.04.03.023846In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

1-(4-methylbenzenesulfonyl)-1H-1,3-benzodiazol-2-amineCAS 799264-47-4
Tma-dphCAS 115534-33-3
Lumateperone TosylateCAS 1187020-80-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 21829-25-4NifedipineCAS 104-31-4BenzonatateCAS 22916-47-8MiconazoleCAS 122-11-2SulfadimethoxineCAS 154-42-72-amino-7H-purine-6-thiolCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 1156-19-0

What are the key identifiers for Tolazamide (CAS 1156-19-0)?

Tolazamide is identified by CAS 1156-19-0, with molecular formula C14H21N3O3S, molecular weight 311.4, InChIKey OUDSBRTVNLOZBN-UHFFFAOYSA-N.

Does CAS 1156-19-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Nuclear factor NF-kappa-B p105 subunit, Cytochrome P450 3A4, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, Alpha-2A adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1156-19-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Tolazamide?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 1156-19-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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