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Home/Compounds/CAS 117-89-5
Formula C21H24F3N3SMW 407.5Research-use catalog entryCOA/SDS by request

Trifluoperazine

CAS Number: 117-89-5

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Loading RDKit molecule structure...
InChIKey: ZEWQUBUPAILYHI-UHFFFAOYSA-NC21H24F3N3S | MW 407.5

Chemical Absolute Identifiers

CAS Number

117-89-5

PubChem CID

5566

Molecular Formula

C21H24F3N3S

Molecular Weight

407.5 g/mol

Exact Mass

407.164303

InChIKey

ZEWQUBUPAILYHI-UHFFFAOYSA-N

IUPAC Name

10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine

SMILES String

CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F

Physical Properties

pKa

1

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Trifluoperazine (CAS 117-89-5) is listed in the Advanced Chemicals portfolio, with molecular formula C21H24F3N3S and molecular weight 407. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Natural Product ResearchSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: D(2) dopamine receptor (Rattus norvegicus) — 4 assays; D(2) dopamine receptor (Homo sapiens) — 4 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 4 assays; D(3) dopamine receptor (Homo sapiens) — 4 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

D(2) dopamine receptor

Rattus norvegicus · SINGLE PROTEIN · 4 qualifying assays · 2 documents · best pChEMBL 9.27

Experimental evidence source: ChEMBL

D(2) dopamine receptor

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 7.83

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 2 documents · best pChEMBL 7.78

Experimental evidence source: ChEMBL

D(3) dopamine receptor

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 7.69

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 7.26

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Stability and reactivity.
  • Carbon monoxide, carbon dioxide, hydrogen fluoride, nitrogen oxides, sulfur oxides.

Disposal

  • The product The remaining and non-recyclable solutions should be handed over to a licensed company for disposal.
  • Contact a professional institution with a waste disposal license to dispose of this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus during firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Trifluoperazine

Names & Synonyms

TrifluperazineTrifluoroperazineTrifluoperazinTriperazineTrifluoperazina
Show all synonyms
FlurazineTriflurinTrifluoromethylperazineTrifluoperazinumApo-TrifluoperazineTriftazinRP 7623EskazinylModalinaTrifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-JatroneuralTriphthazine
External Identifiers
EC NUMBER: 204-219-4DSSTOX SUBSTANCE ID: DTXSID1046928CHEMBL ID: CHEMBL422CHEBI ID: CHEBI:45951UNII: 214IZI85K3DRUGBANK ID: DB00831HMDB ID: HMDB0014969KEGG ID: C07168KEGG ID: D08636METABOLOMICS WORKBENCH ID: 43119NCI THESAURUS CODE: C62084PHARMGKB ID: PA451771RXCUI: 10800WIKIDATA ID: Q1752915
Experimental Spectrum References
ATR-IR Spectra — Forensic Spectral ResearchRaman SpectraUV Spectra
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1039/d4md00449cUnderstanding the mechanisms of antimicrobial resistance and potential therapeutic approaches against the Gram-negative pathogen <i>Acinetobacter baumannii</i>.PMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 39386059Understanding the mechanisms of antimicrobial resistance and potential therapeutic approaches against the Gram-negative pathogen <i>Acinetobacter baumannii</i>.DOI 10.1016/j.bmc.2023.117212Targeting mycobacterial membranes and membrane proteins: Progress and limitations.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 36804747Targeting mycobacterial membranes and membrane proteins: Progress and limitations.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 21829-25-4NifedipineCAS 23593-75-1ClotrimazoleCAS 132539-06-1OlanzapineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 117-89-5

What are the key identifiers for Trifluoperazine (CAS 117-89-5)?

Trifluoperazine is identified by CAS 117-89-5, with molecular formula C21H24F3N3S, molecular weight 407.5, InChIKey ZEWQUBUPAILYHI-UHFFFAOYSA-N.

Does CAS 117-89-5 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with D(2) dopamine receptor, D(2) dopamine receptor, 5-hydroxytryptamine receptor 2A, D(3) dopamine receptor, Alpha-1A adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 117-89-5?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Trifluoperazine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 117-89-5 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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