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Home/Compounds/CAS 1188-21-2
Formula C8H15NO3MW 173.21Research-use catalog entryCOA/SDS by request

N-Acetyl-L-leucine

CAS Number: 1188-21-2

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Loading RDKit molecule structure...
InChIKey: WXNXCEHXYPACJF-ZETCQYMHSA-NC8H15NO3 | MW 173.21

Chemical Absolute Identifiers

CAS Number

1188-21-2

PubChem CID

70912

Molecular Formula

C8H15NO3

Molecular Weight

173.21 g/mol

Exact Mass

173.105193

InChIKey

WXNXCEHXYPACJF-ZETCQYMHSA-N

IUPAC Name

(2S)-2-acetamido-4-methylpentanoic acid

SMILES String

CC(C)C[C@@H](C(=O)O)NC(=O)C

Physical Properties

Water Solubility

8.1 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

N-Acetyl-L-leucine (CAS 1188-21-2) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C8H15NO3 and molecular weight 173. 21 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • The product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Use personal protective equipment and emergency procedures.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

N-Acetyl-L-leucine

Names & Synonyms

N-AcetylleucineL-Acetylleucine(S)-2-Acetamido-4-methylpentanoic acidN-acetyl-leucineLevacetylleucine
Show all synonyms
Leucine, N-acetyl-, L-n-acetyl leucineN-ACETYL-L-(-)-LEUCINEAQNEURSAACETYLLEUCINE, (S)-acetyl-L-leucineAc-Leu-OHn-acetyl-L-leucinL-Leucine, N-acetyl-(2S)-2-acetamido-4-methyl-pentanoic acidACETYLLEUCINE, L-(2S)-2-(acetylamino)-4-methylpentanoic acidLevacetylleucine (USAN)N-acetyl-Leu
External Identifiers
EC NUMBER: 214-706-3DSSTOX SUBSTANCE ID: DTXSID6045870CHEMBL ID: CHEMBL56021CHEBI ID: CHEBI:17786UNII: E915HL7K2ODRUGBANK ID: DB16956HMDB ID: HMDB0011756KEGG ID: C02710KEGG ID: D12967METABOLOMICS WORKBENCH ID: 41523NCI THESAURUS CODE: C211767PHARMGKB ID: PA166400081RXCUI: 2375522WIKIDATA ID: Q63395724
Experimental Spectrum References
13C NMR Spectra — Sigma-Aldrich Co. LLC.1H NMR Spectra — Sigma-Aldrich Co. LLC.ATR-IR Spectra
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.1101/2020.04.03.023846In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replicationDOI 10.1101/2020.04.21.054387Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethan-1-aminium (2S)-2-acetamido-4-methylpentanoateCAS 608141-43-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 102146-07-6DpcpxCAS 104227-87-4FamciclovirCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 1188-21-2

What are the key identifiers for N-Acetyl-L-leucine (CAS 1188-21-2)?

N-Acetyl-L-leucine is identified by CAS 1188-21-2, with molecular formula C8H15NO3, molecular weight 173.21, InChIKey WXNXCEHXYPACJF-ZETCQYMHSA-N.

Can I request a COA for CAS 1188-21-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for N-Acetyl-L-leucine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 1188-21-2 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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