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Home/Compounds/CAS 120068-37-3
Formula C12H4Cl2F6N4OSMW 437.1Research-use catalog entryCOA/SDS by request

Fipronil

CAS Number: 120068-37-3

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Loading RDKit molecule structure...
InChIKey: ZOCSXAVNDGMNBV-UHFFFAOYSA-NC12H4Cl2F6N4OS | MW 437.1

Chemical Absolute Identifiers

CAS Number

120068-37-3

PubChem CID

3352

Molecular Formula

C12H4Cl2F6N4OS

Molecular Weight

437.1 g/mol

Exact Mass

435.938706

InChIKey

ZOCSXAVNDGMNBV-UHFFFAOYSA-N

IUPAC Name

5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile

SMILES String

C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F

Physical Properties

Melting Point

2–201 °C

Density

1.48 g/cm³

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Fipronil (CAS 120068-37-3) is listed in the Advanced Chemicals portfolio, with molecular formula C12H4Cl2F6N4OS and molecular weight 437. 10 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Gamma-aminobutyric acid receptor subunit beta-3 (Homo sapiens) — 3 assays; Nuclear receptor ROR-gamma (Mus musculus) — 2 assays; Nuclear receptor subfamily 1 group I member 2 (Homo sapiens) — 2 assays; Cytochrome P450 3A4 (Homo sapiens) — 2 assays; Peripheral myelin protein 22 (Rattus norvegicus) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Gamma-aminobutyric acid receptor subunit beta-3

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 8.62

Experimental evidence source: ChEMBL

Nuclear receptor ROR-gamma

Mus musculus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.25

Experimental evidence source: ChEMBL

Nuclear receptor subfamily 1 group I member 2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.82

Experimental evidence source: ChEMBL

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.6

Experimental evidence source: ChEMBL

Peripheral myelin protein 22

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and stability.
  • Carbon monoxide, carbon dioxide, hydrogen chloride, hydrogen fluoride, nitrogen oxides, sulfur oxides.

Disposal

  • Waste: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional institution with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus during firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Fipronil

Names & Synonyms

TermidorRM 1601MB 460305-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-((trifluoromethyl)sulfinyl)-1h-pyrazole-3-carbonitrile5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile
Show all synonyms
FRONTLINEFipronil (ema epar: veterinary)BROADLINE COMPONENT FIPRONIL(RS)-5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile1H-Pyrazole-3-carbonitrile, 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-((trifluoromethyl)sulfinyl)-5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-trifluoromethanesulfinyl-1H-pyrazole-3-carbonitrile1H-Pyrazole-3-carbonitrile, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethanesulfinyl-1H-pyrazole-3-carbonitrile5-amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoromethylsulfinylpyrazole-3-carbonitile5-AMINO-1-(2,6-DICHLORO-alpha,alpha,alpha-TRIFLUORO-P-TOLYL)-4-((TRIFLUOROMETHYL)SULFINYL)PYRAZOLE-3-CARBONITRILEC12H4Cl2F6N4OSFipronil [ISO](+/-)-Fipronil
External Identifiers
EC NUMBER: 424-610-5DSSTOX SUBSTANCE ID: DTXSID4034609CHEMBL ID: CHEMBL101326CHEBI ID: CHEBI:83394UNII: QGH063955FHMDB ID: HMDB0252265ICSC NUMBER: 1503KEGG ID: C11099KEGG ID: D01042METABOLOMICS WORKBENCH ID: 53175NCI THESAURUS CODE: C74341WIKIDATA ID: Q415933
Experimental Spectrum References
13C NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1021/acs.jmedchem.0c02245Designing Out PXR Activity on Drug Discovery Projects: A Review of Structure-Based Methods, Empirical and Computational Approaches.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 34003642Designing Out PXR Activity on Drug Discovery Projects: A Review of Structure-Based Methods, Empirical and Computational Approaches.DOI 10.1101/2020.04.03.023846In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replicationDOI 10.1101/2020.04.21.054387Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

5-Amino-1-(2,6-dimethylphenyl)-1H-pyrazole-4-carbonitrileCAS 792952-99-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 2926-29-6sodium trifluoromethanesulfinateCAS 21829-25-4NifedipineCAS 50-65-7NiclosamideCAS 97-18-7BithionolCAS 106308-44-5RufinamideCAS 23593-75-1ClotrimazoleCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 120068-37-3

What are the key identifiers for Fipronil (CAS 120068-37-3)?

Fipronil is identified by CAS 120068-37-3, with molecular formula C12H4Cl2F6N4OS, molecular weight 437.1, InChIKey ZOCSXAVNDGMNBV-UHFFFAOYSA-N.

Does CAS 120068-37-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Gamma-aminobutyric acid receptor subunit beta-3, Nuclear receptor ROR-gamma, Nuclear receptor subfamily 1 group I member 2, Cytochrome P450 3A4, Peripheral myelin protein 22. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 120068-37-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Fipronil?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 120068-37-3 available for quotation?

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