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Home/Compounds/CAS 121-34-6
Formula C8H8O4MW 168.15Research-use catalog entryCOA/SDS by request

Vanillic Acid

CAS Number: 121-34-6

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Available Options

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1 kg
Purity
98%
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100 g
Purity
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25 g
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Loading RDKit molecule structure...
InChIKey: WKOLLVMJNQIZCI-UHFFFAOYSA-NC8H8O4 | MW 168.15

Chemical Absolute Identifiers

CAS Number

121-34-6

PubChem CID

8468

Molecular Formula

C8H8O4

Molecular Weight

168.15 g/mol

Exact Mass

168.042259

InChIKey

WKOLLVMJNQIZCI-UHFFFAOYSA-N

IUPAC Name

4-hydroxy-3-methoxybenzoic acid

SMILES String

COC1=C(C=CC(=C1)C(=O)O)O

Physical Properties

Melting Point

211.5 °C

pKa

4.51

Show more physical data

Vapor Pressure

Estimated very low; unit not specified

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Vanillic Acid (CAS 121-34-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C8H8O4 and molecular weight 168. 15 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Estrogen receptor (Homo sapiens) — 2 assays; Tyrosinase (Agaricus bisporus) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Estrogen receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Tyrosinase

Agaricus bisporus · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction stability.
  • Carbon monoxide, carbon dioxide.

Disposal

  • Waste product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
Show additional safety reference fields

Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Use personal protective equipment and emergency procedures.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Vanillic Acid

Names & Synonyms

Acide vanilliqueBenzoic acid, 4-hydroxy-3-methoxy-3-Methoxy-4-hydroxybenzoic acidFEMA NO. 3988Acid, Vanillic
Show all synonyms
4 Hydroxy 3 methoxybenzoic Acidp Hydroxy m methoxy benzoic Acidp-Hydroxy-m-methoxy-benzoic AcidAcid, 4-Hydroxy-3-methoxybenzoicAcid, p-Hydroxy-m-methoxy-benzoicp-Vanillic acidVanillicAcidm-Anisic acid, 4-hydroxy-4-hydroxy-3-methoxy-Benzoic acidProtocatechuic acid, 3-methyl ester4-hydroxy-3-methoxy benzoic acidVAVA (VAN)VNL
External Identifiers
EC NUMBER: 204-466-8DSSTOX SUBSTANCE ID: DTXSID6059522CHEMBL ID: CHEMBL120568CHEBI ID: CHEBI:30816UNII: GM8Q3JM2Y8DRUGBANK ID: DB02130HMDB ID: HMDB0000484KEGG ID: C06672METABOLOMICS WORKBENCH ID: 37271WIKIDATA ID: Q419672
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR SpectraFTIR Spectra — Bio-Rad Laboratories, Inc.Raman Spectra — Forensic Spectral ResearchUV-VIS SpectraVapor Phase IR Spectra
Literature & Patent References
DOI 10.1021/acs.jmedchem.5c004183,5-Dihydroxybenzoic Acid as a Potent Inhibitor of Tyrosine Phenol-Lyase Decreases Fecal Phenol Levels in Mice.PMID 401731063,5-Dihydroxybenzoic Acid as a Potent Inhibitor of Tyrosine Phenol-Lyase Decreases Fecal Phenol Levels in Mice.DOI 10.1016/j.bmcl.2023.129386Phytochemical investigation of Asarum sieboldii var. seoulense and the phenotypic profiles of its constituents against a Parkinson's Disease olfactory cell line.PMID 37355024Phytochemical investigation of Asarum sieboldii var. seoulense and the phenotypic profiles of its constituents against a Parkinson's Disease olfactory cell line.DOI 10.1016/j.bmc.2022.117000Biosynthesis of vanillic acid by Ochrobactrum anthropi and its applications.DOI 10.1016/j.bmcl.2022.128722Polyphenolic compounds: Synthesis, assessment of antimicrobial effect and enzymes inhibition against important medicinal enzymes with computational details.PMID 35395370Polyphenolic compounds: Synthesis, assessment of antimicrobial effect and enzymes inhibition against important medicinal enzymes with computational details.PMID 36095944Biosynthesis of vanillic acid by Ochrobactrum anthropi and its applications.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

Benzyl 4-(benzyloxy)-3-methoxybenzoateCAS 91203-74-6
Methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)methoxy]benzoateCAS 635678-09-0
2-Amino-4-(benzyloxy)-5-methoxybenzamideCAS 60547-98-0
Tert-butyl 4-[2-methoxy-4-(methoxycarbonyl)phenoxymethyl]piperidine-1-carboxylateCAS 906565-52-4
Benzyl 4-(benzyloxy)-5-methoxy-2-nitrobenzoateCAS 205259-40-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 99-50-3Protocatechuic AcidCAS 14371-10-9CinnamaldehydeCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 121-34-6

What are the key identifiers for Vanillic Acid (CAS 121-34-6)?

Vanillic Acid is identified by CAS 121-34-6, with molecular formula C8H8O4, molecular weight 168.15, InChIKey WKOLLVMJNQIZCI-UHFFFAOYSA-N.

Does CAS 121-34-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Estrogen receptor, Tyrosinase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 121-34-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Vanillic Acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 121-34-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

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