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Home/Compounds/CAS 121032-29-9
Formula C11H15N5O5MW 297.27Research-use catalog entryCOA/SDS by request

Nelarabine

CAS Number: 121032-29-9

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Loading RDKit molecule structure...
InChIKey: IXOXBSCIXZEQEQ-UHTZMRCNSA-NC11H15N5O5 | MW 297.27

Chemical Absolute Identifiers

CAS Number

121032-29-9

PubChem CID

3011155

Molecular Formula

C11H15N5O5

Molecular Weight

297.27 g/mol

Exact Mass

297.107319

InChIKey

IXOXBSCIXZEQEQ-UHTZMRCNSA-N

IUPAC Name

(2R,3S,4S,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

SMILES String

COc1nc(N)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O

Physical Properties

Water Solubility

13.9 g/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Nelarabine (CAS 121032-29-9) is listed in the Advanced Chemicals portfolio, with molecular formula C11H15N5O5 and molecular weight 297. 27 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Nelarabine

Names & Synonyms

NelzarabineArranonAtriance506UAttriance
Show all synonyms
2-Amino-6-methoxypurine arabinosidecompound 506U78Nelarabina2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine(2R,3S,4S,5R)-2-(2-amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol(2R,3S,4S,5R)-2-(hydroxymethyl)-5-(2-imino-6-methoxy-3,9-dihydro-2H-purin-9-yl)oxolane-3,4-diolnelarabinumnelarabine injection2-Amino, 6-Methoxypurine Arabinoside9-beta-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine(2R,3S,4S,5R)-2-(2-Amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolNelarabine (Arranon)9H-Purin-2-amine, 9-b-D-arabinofuranosyl-6-methoxy-GW 506U78
External Identifiers
EC NUMBER: 642-916-9DSSTOX SUBSTANCE ID: DTXSID6046842CHEMBL ID: CHEMBL1201112CHEBI ID: CHEBI:63612UNII: 60158CV180DRUGBANK ID: DB01280HMDB ID: HMDB0015401KEGG ID: D05134METABOLOMICS WORKBENCH ID: 43477NCI THESAURUS CODE: C1704PHARMGKB ID: PA164752425RXCUI: 274771WIKIDATA ID: Q1216264
Literature & Patent References
DOI 10.1016/j.bmcl.2025.130110Nucleoside antiviral agents with atypical structures and new targets.PMID 39864529Nucleoside antiviral agents with atypical structures and new targets.DOI 10.1016/j.ejmech.2021.113218FDA-approved pyrimidine-fused bicyclic heterocycles for cancer therapy: Synthesis and clinical application.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 33540357FDA-approved pyrimidine-fused bicyclic heterocycles for cancer therapy: Synthesis and clinical application.DOI 10.1101/2020.04.03.023846In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replicationDOI 10.1101/2020.04.21.054387Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

2-Amino-6-chloropurine ribosideCAS 2004-07-1
FludarabineCAS 21679-14-1
2-HydrazinoadenosineCAS 15763-11-8
IsoguanosineCAS 1818-71-9
VidarabineCAS 5536-17-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 2004-07-12-Amino-6-chloropurine ribosideCAS 21679-14-1FludarabineCAS 15763-11-82-HydrazinoadenosineCAS 1818-71-9IsoguanosineCAS 5536-17-4VidarabineCAS 100643-71-8DesloratadineCAS 10083-24-6PiceatannolCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 121032-29-9

What are the key identifiers for Nelarabine (CAS 121032-29-9)?

Nelarabine is identified by CAS 121032-29-9, with molecular formula C11H15N5O5, molecular weight 297.27, InChIKey IXOXBSCIXZEQEQ-UHTZMRCNSA-N.

Does CAS 121032-29-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 121032-29-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Nelarabine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 121032-29-9 available for quotation?

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