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Home/Compounds/CAS 1218779-75-9
Formula C25H27N5O4SMW 493.6Research-use catalog entryCOA/SDS by request

Rivoceranib Mesylate

CAS Number: 1218779-75-9

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Loading RDKit molecule structure...
InChIKey: FYJROXRIVQPKRY-UHFFFAOYSA-NC25H27N5O4S | MW 493.6

Chemical Absolute Identifiers

CAS Number

1218779-75-9

PubChem CID

45139106

Molecular Formula

C25H27N5O4S

Molecular Weight

493.6 g/mol

Exact Mass

493.178376

InChIKey

FYJROXRIVQPKRY-UHFFFAOYSA-N

IUPAC Name

N-[4-(1-cyanocyclopentyl)phenyl]-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide;methanesulfonic acid

SMILES String

CS(=O)(=O)O.N#CC1(c2ccc(NC(=O)c3cccnc3NCc3ccncc3)cc2)CCCC1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Rivoceranib Mesylate (CAS 1218779-75-9) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C25H27N5O4S and molecular weight 493. 60 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow

Safety & Handling

Safety and handling reference content is available through documentation requests.

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Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Rivoceranib Mesylate

Names & Synonyms

ApatinibApatinib Mesylate3-Pyridinecarboxamide, N-(4-(1-cyanocyclopentyl)phenyl)-2-((4-pyridinylmethyl)amino)-, methanesulfonate (1:1)Aitan3-Pyridinecarboxamide, N-[4-(1-cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-, methanesulfonate (1:1)
Show all synonyms
3-Pyridinecarboxamide, N-(4-(1-cyanocyclopentyl)phenyl)-2-((4-methyl-3-pyridinyl)amino)-N-(4-(1-cyanocyclopentyl)phenyl)-2-((pyridin-4-ylmethyl)amino)nicotinamide methanesulfonateRivoceranib mesylate (USAN)RIVOCERANIB MESYLATE [USAN]YN 968D1Apatinib Mesylate?Alitan (TN)Apatinib (free base)?Protein Tyrosine Kinase InhibitorsApatinib (registered name in China)RIVOCERANIB MESYLATE [WHO-DD]N-(4-(1-Cyanocyclopentyl)phenyl)-2-((pyridin-4-ylmethyl)amino)nicotinamide MesylateN-(4-(1-cyanocyclopentyl)phenyl)-2-(pyridin-4-ylmethylamino)nicotinamide mesylateMethanesulfonic acid--N-[4-(1-cyanocyclopentyl)phenyl]-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide (1/1)N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide monomethanesulfonate salt
External Identifiers
EC NUMBER: 881-162-7DSSTOX SUBSTANCE ID: DTXSID80153427CHEMBL ID: CHEMBL3545414UNII: TK02X14ASJKEGG ID: D11289NCI THESAURUS CODE: C74012PHARMGKB ID: PA166316721WIKIDATA ID: Q4779233
Literature & Patent References
DOI 10.1016/j.bmc.2023.117561Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors.PMID 38157838Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors.DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1016/j.bmc.2016.03.004Synthetic approaches to the 2014 new drugs.PMID 27020685Synthetic approaches to the 2014 new drugs.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

2-chloro-N-(4-(1-cyanocyclopentyl)phenyl)nicotinamideCAS 1158560-99-6
1-PhenylcyclopentanecarbonitrileCAS 77-57-6
1-(4-Aminophenyl)cyclopentanecarbonitrileCAS 115279-73-7
1-(4-Nitrophenyl)cyclopentane-1-carbonitrileCAS 91392-33-5

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1158560-99-62-chloro-N-(4-(1-cyanocyclopentyl)phenyl)nicotinamideCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 1218779-75-9

What are the key identifiers for Rivoceranib Mesylate (CAS 1218779-75-9)?

Rivoceranib Mesylate is identified by CAS 1218779-75-9, with molecular formula C25H27N5O4S, molecular weight 493.6, InChIKey FYJROXRIVQPKRY-UHFFFAOYSA-N.

Can I request a COA for CAS 1218779-75-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Rivoceranib Mesylate?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 1218779-75-9 available for quotation?

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