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Home/Compounds/CAS 123-78-4
Formula C18H37NO2MW 299.5Research-use catalog entryCOA/SDS by request

Sphingosine

CAS Number: 123-78-4

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Loading RDKit molecule structure...
InChIKey: WWUZIQQURGPMPG-KRWOKUGFSA-NC18H37NO2 | MW 299.5

Chemical Absolute Identifiers

CAS Number

123-78-4

PubChem CID

5280335

Molecular Formula

C18H37NO2

Molecular Weight

299.5 g/mol

Exact Mass

299.282429

InChIKey

WWUZIQQURGPMPG-KRWOKUGFSA-N

IUPAC Name

(E,2S,3R)-2-aminooctadec-4-ene-1,3-diol

SMILES String

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Sphingosine (CAS 123-78-4) is listed in the Advanced Chemicals portfolio, with molecular formula C18H37NO2 and molecular weight 299. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Natural Product ResearchSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Sphingosine kinase 2 (Homo sapiens) — 2 assays; Sphingosine kinase 1 (Homo sapiens) — 2 assays; Prelamin-A/C (Homo sapiens) — 2 assays; Ubiquitin-conjugating enzyme E2 N (Homo sapiens) — 2 assays; Geminin (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Sphingosine kinase 2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 5.81

Experimental evidence source: ChEMBL

Sphingosine kinase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 5.41

Experimental evidence source: ChEMBL

Prelamin-A/C

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.3

Experimental evidence source: ChEMBL

Ubiquitin-conjugating enzyme E2 N

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.21

Experimental evidence source: ChEMBL

Geminin

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 4.8

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Sphingosine

Names & Synonyms

D-erythro-SphingosineD-Sphingosine4-SphingenineSphingenine(4E)-Sphingenine
Show all synonyms
(2S,3R,4E)-2-Amino-4-octadecene-1,3-diol4-trans-Sphingenine(2S,3R)-2-aminooctadec-4-ene-1,3-diol(E)-2-Amino-4-octadecan-1,3-diol(4E)-sphing-4-enine4-Octadecene-1,3-diol, 2-amino-, (R-(R*,S*-(E)))-2-amino-4-octadecene-1,3-diol4 Sphingenine4-Octadecene-1,3-diol, 2-amino-, [R-[R*,S*-(E)]]-trans-D-erythro-2-Amino-4-octadecene-1,3-diol(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diolD-erythro-Sphingosine (synthetic)
External Identifiers
EC NUMBER: 204-651-3DSSTOX SUBSTANCE ID: DTXSID90861763CHEMBL ID: CHEMBL67166CHEBI ID: CHEBI:16393UNII: 0Y6SVQ612QUNII: NGZ37HRE42DRUGBANK ID: DB03203HMDB ID: HMDB0000252KEGG ID: C00319METABOLOMICS WORKBENCH ID: 30474WIKIDATA ID: Q46298Sphing-4-eninetrans-4-Sphingenine
Experimental Spectrum References
13C NMR Spectra1H NMR Spectra
Literature & Patent References
DOI 10.6019/EOS300108ECBD screening data for assay EOS300108DOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1016/j.bmc.2016.07.038Effects of stereochemistry, saturation, and hydrocarbon chain length on the ability of synthetic constrained azacyclic sphingolipids to trigger nutrient transporter down-regulation, vacuolation, and cell death.PMID 27475534Effects of stereochemistry, saturation, and hydrocarbon chain length on the ability of synthetic constrained azacyclic sphingolipids to trigger nutrient transporter down-regulation, vacuolation, and cell death.DOI 10.1016/j.ejmech.2011.09.010Diastereoselective synthesis and bioactivity of long-chain anti-2-amino-3-alkanols.PMID 21955681Diastereoselective synthesis and bioactivity of long-chain anti-2-amino-3-alkanols.DOI 10.1016/j.bmcl.2010.01.068Synthesis and chain-dependent antifungal activity of long-chain 2H-azirine-carboxylate esters related to dysidazirine.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

trans-2-Octenoic acidCAS 1871-67-6
DecanalCAS 112-31-2
TrilinoleinCAS 537-40-6
Decanoic AcidCAS 334-48-5
Tridecanoic acidCAS 638-53-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 65646-68-6FenretinideCAS 10083-24-6PiceatannolCAS 23593-75-1ClotrimazoleCAS 26993-30-6Sphingosine 1-PhosphateCAS 62996-74-1StaurosporineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 123-78-4

What are the key identifiers for Sphingosine (CAS 123-78-4)?

Sphingosine is identified by CAS 123-78-4, with molecular formula C18H37NO2, molecular weight 299.5, InChIKey WWUZIQQURGPMPG-KRWOKUGFSA-N.

Does CAS 123-78-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Sphingosine kinase 2, Sphingosine kinase 1, Prelamin-A/C, Ubiquitin-conjugating enzyme E2 N, Geminin. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 123-78-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Sphingosine?

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Is CAS 123-78-4 available for quotation?

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